| 51 |
22281494 | Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes. | 2012 Feb 10 |
2 |
| 52 |
22333157 | mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes. | 2012 May 15 |
1 |
| 53 |
22842983 | Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression. | 2012 Sep |
1 |
| 54 |
22973301 | Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2. | 2012 |
5 |
| 55 |
23272222 | Regulated in development and DNA damage responses -1 (REDD1) protein contributes to insulin signaling pathway in adipocytes. | 2012 |
1 |
| 56 |
20936651 | Comparison of intracellular signalling by insulin and the hypermitogenic AspB10 analogue in MCF-7 breast adenocarcinoma cells. | 2011 May |
1 |
| 57 |
21046356 | Beta cell function during rapamycin monotherapy in long-term type 1 diabetes. | 2011 Feb |
1 |
| 58 |
21296326 | Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry. | 2011 Apr 15 |
1 |
| 59 |
21602475 | Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake. | 2011 Aug |
1 |
| 60 |
21672148 | Rapamycin-induced hypophosphatemia and insulin resistance are associated with mTORC2 activation and Klotho expression. | 2011 Aug |
2 |
| 61 |
21854819 | Insulin-induced neurite-like process outgrowth: acceleration of tau protein synthesis via a phosphoinositide 3-kinase~mammalian target of rapamycin pathway. | 2011 Nov |
1 |
| 62 |
25961241 | Crosstalk with insulin and dependence on PI3K/Akt/mTOR rather than MAPK pathways in upregulation of basal growth following long-term oestrogen deprivation in three human breast cancer cell lines. | 2011 Mar 1 |
1 |
| 63 |
19864431 | Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation. | 2010 Jan 1 |
1 |
| 64 |
19940100 | Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle. | 2010 Feb |
1 |
| 65 |
20138985 | Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1. | 2010 Jun |
1 |
| 66 |
20203102 | Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes. | 2010 Apr |
1 |
| 67 |
20299475 | Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue. | 2010 Jun |
4 |
| 68 |
20484410 | cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4. | 2010 Jul |
1 |
| 69 |
21041974 | Impact of insulin-treated diabetes and hemodialysis on long-term clinical outcomes following sirolimus-eluting stent deployment. Insights from a sub-study of the Cypher Stent Japan Post-Marketing Surveillance(Cypher J-PMS) Registry. | 2010 Nov |
1 |
| 70 |
19168580 | The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation. | 2009 Apr |
2 |
| 71 |
19190264 | Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes. | 2009 Apr |
1 |
| 72 |
19356713 | A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. | 2009 Apr |
1 |
| 73 |
19567519 | Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases. | 2009 Sep |
1 |
| 74 |
19651294 | Mammalian target of rapamycin and diabetes: what does the current evidence tell us? | 2009 Jul-Aug |
1 |
| 75 |
20847591 | Regulation of SREBP1c expression by mTOR signaling in hepatocytes. | 2009 Nov 24 |
1 |
| 76 |
17993646 | Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. | 2008 Jan 11 |
2 |
| 77 |
18093179 | Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway. | 2008 Jan |
2 |
| 78 |
18174523 | mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. | 2008 Apr |
3 |
| 79 |
18303120 | Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation. | 2008 May |
2 |
| 80 |
18431361 | Regulated insulin delivery from human epidermal cells reverses hyperglycemia. | 2008 Jun |
2 |
| 81 |
18586400 | Frequency modulation of synchronized Ca(2+) spikes in cultured hippocampal networks through mTOR. | 2008 Aug 15 |
1 |
| 82 |
16952420 | Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70(S6K) in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB. | 2007 Jan |
2 |
| 83 |
17244624 | Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1. | 2007 Mar 16 |
2 |
| 84 |
17329620 | The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man. | 2007 Jun |
1 |
| 85 |
17353769 | In vivo and in vitro effect of sirolimus on insulin secretion. | 2007 Mar 15 |
6 |
| 86 |
17371596 | Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes. | 2007 Mar 19 |
2 |
| 87 |
17379645 | Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway. | 2007 Jul |
2 |
| 88 |
17698027 | Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation. | 2007 Sep 15 |
1 |
| 89 |
17920355 | Comparison of outcomes using sirolimus-eluting stenting in diabetic versus nondiabetic patients with comparison of insulin versus non-insulin therapy in the diabetic patients. | 2007 Oct 15 |
1 |
| 90 |
16396989 | Differential mitogenic signaling in insulin receptor-deficient fetal pancreatic beta-cells. | 2006 Apr |
1 |
| 91 |
16455781 | Regulation of hepatic insulin-like growth factor-binding protein-1 gene expression by insulin: central role for mammalian target of rapamycin independent of forkhead box O proteins. | 2006 May |
2 |
| 92 |
16506055 | Insulin activates hypoxia-inducible factor-1alpha in human and rat vascular smooth muscle cells via phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways: impairment in insulin resistance owing to defects in insulin signalling. | 2006 May |
1 |
| 93 |
16545079 | Regulation of protein synthesis by insulin. | 2006 Apr |
1 |
| 94 |
16651733 | Regulators for blood glucose level affect gene expression of aquaporin 3. | 2006 May |
1 |
| 95 |
16680182 | Immunosuppression for islet transplantation. | 2006 Apr |
1 |
| 96 |
16763566 | The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. | 2006 Jun 21 |
1 |
| 97 |
16896936 | The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells. | 2006 Oct |
2 |
| 98 |
17077083 | Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway. | 2006 Dec 29 |
1 |
| 99 |
17125709 | [Efficacy of sirolimus-eluting stent implantation in diabetic patients with very small vessels (< or = 2.25 mm). Insights from the DIABETES trial]. | 2006 Oct |
1 |
| 100 |
15576463 | Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes. | 2005 Mar |
4 |