Title : Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.

Pub. Date : 2010 Jun

PMID : 20138985






1 Functional Relationships(s)
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1 Inhibition of mTORC1 by rapamycin or amino acid deprivation partially abrogated insulin-mediated PRAS40-Ser183 phosphorylation in cultured cell lines. Sirolimus insulin Homo sapiens