Disulfides

insulin ; Homo sapiens







246 Article(s)
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Title
Pub. Year
#Total Relationships
151 11090689 Increased production of human proinsulin in the periplasmic space of Escherichia coli by fusion to DsbA. 2001 Nov 30 7
152 11168891 Synthesis and conformational analysis of the insulin-like 4 gene product. 2001 Jan 2
153 11258877 Putative disulfide-forming pathway of porcine insulin precursor during its refolding in vitro. 2001 Mar 6 1
154 11591149 Hierarchical protein folding: asymmetric unfolding of an insulin analogue lacking the A7-B7 interchain disulfide bridge. 2001 Oct 16 3
155 12040418 Unfolding of Recombinant Single-chain Insulin in Denaturants Containing Thiol Reagents. 2001 1
156 11046093 Hypoglycemic effect of insulin-transferrin conjugate in streptozotocin-induced diabetic rats. 2000 Nov 2
157 11083061 Three-dimensional solution structure of a disulfide bond isomer of the human insulin-like growth factor-I. 2000 Oct 2
158 11112528 Hierarchical protein "un-design": insulin's intrachain disulfide bridge tethers a recognition alpha-helix. 2000 Dec 19 2
159 9668102 Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian protein of 32 kDa. 1998 Jul 24 1
160 9688536 Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes. 1998 Jul 3 3
161 9006939 Cloning and expression of a novel mammalian thioredoxin. 1997 Jan 31 1
162 9037180 Expression, purification and characterization of recombinant human proinsulin. 1997 Feb 3 1
163 9388210 Inhibition of insulin receptor activation by insulin-like growth factor binding proteins. 1997 Dec 5 1
164 9388228 Cloning, expression, and characterization of a novel Escherichia coli thioredoxin. 1997 Dec 5 1
165 8753066 [Studies on development of disulfide bond forming reaction and the application to regioselective disulfide formation]. 1996 Jun 3
166 8765230 Characteristic, activity and conformational studies of [A6-Ser, A11-Ser]-insulin. 1996 Aug 15 3
167 8961144 Transcellular delivery of an insulin-transferrin conjugate in enterocyte-like Caco-2 cells. 1996 Dec 1
168 7657617 Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility. 1995 Sep 1 5
169 7819243 Interaction of alpha-crystallin with spin-labeled peptides. 1995 Jan 17 1
170 7852537 Insulin degradation by adipose tissue is increased in human obesity. 1995 Feb 1
171 7727378 Insulin-like compounds related to the amphioxus insulin-like peptide. 1994 Sep 20 1
172 7804129 Intra-A chain disulfide bond (A6-11) of insulin is essential for displaying its activity. 1994 Aug 3
173 7811279 Unusual insulin binding to cells expressing an insulin receptor mutated at cysteine 524. 1994 Dec 30 1
174 7983787 [The structure function relationship in the human insulin receptor]. 1994 Oct 1
175 8064238 Allele specificity of structural requirement for peptides bound to HLA-DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome. 1994 Sep 1 4
176 8140052 Moisture-induced aggregation of lyophilized insulin. 1994 Jan 2
177 8171015 Naturally processed heterodimeric disulfide-linked insulin peptides bind to major histocompatibility class II molecules on thymic epithelial cells. 1994 Apr 26 2
178 8175738 Functional importance of the A chain loop in relaxin and insulin. 1994 May 6 1
179 8199238 Design and synthesis of a protein device that releases insulin in response to glucose concentration. 1994 Jan-Feb 2
180 8257688 Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification. 1993 Dec 14 1
181 8440700 Insulin receptor autophosphorylation occurs asymmetrically. 1993 Feb 25 1
182 1283335 Processing and presentation of insulin. III. Insulin degrading enzyme: a neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells. 1992 Oct 2
183 1316357 The insulin-binding domain of insulin receptor is encoded by exon 2 and exon 3. 1992 Jan 1
184 1320041 Insulin/IGF-I receptor hybrids: a mechanism for increasing receptor diversity. 1992 Feb 1
185 1414126 [Studies on genetic engineering of human insulin-purification and characterization of human proinsulin and insulin]. 1992 Jun 1
186 1438162 Improved insulin stability through amino acid substitution. 1992 Sep 3
187 1730606 (A-C-B) human proinsulin, a novel insulin agonist and intermediate in the synthesis of biosynthetic human insulin. 1992 Jan 5 1
188 1654393 Characterization of a novel receptor in toad retina with dual specificity for insulin and insulin-like growth factor I. 1991 Oct 1
189 1657953 Substitution of arginine for histidine at position 209 in the alpha-subunit of the human insulin receptor. A mutation that impairs receptor dimerization and transport of receptors to the cell surface. 1991 Nov 5 1
190 1940793 Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant. 1991 Nov 1 2
191 2076464 Structural characterization by mass spectrometry of native and recombinant human relaxin. 1990 Nov 1
192 2090118 [Use of thiol sorbents for obtaining human recombinant proinsulin]. 1990 Dec 2
193 2112914 Reaction of insulin with reduced glutathione. 1990 1
194 2194740 Relaxin. 1990 1
195 2531072 Demonstration of an endocrine signaling circuit for insulin in the sponge Geodia cydonium. 1989 Oct 1
196 2540806 Relationship between insulin receptor subunit association and protein kinase activation: insulin-dependent covalent and Mn/MgATP-dependent noncovalent association of alpha beta heterodimeric insulin receptors into an alpha 2 beta 2 heterotetrameric state. 1989 Jan 24 2
197 2684974 Identification of insulin intermediates and sites of cleavage of native insulin by insulin protease from human fibroblasts. 1989 Dec 5 1
198 2692717 Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure, and dynamics. 1989 Dec 12 3
199 2698041 Possible mechanism of inhibition of cartilage alkaline phosphatase by insulin. 1989 Oct-Dec 1
200 2835273 Proposal for a pathway to mediate the metabolic effects of insulin. 1988 1