Arsenic Trioxide

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







13 Article(s)
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1 32305283 Arsenic trioxide-induced p38 MAPK and Akt mediated MCL1 downregulation causes apoptosis of BCR-ABL1-positive leukemia cells. 2020 Apr 17 5
2 30763586 Homoharringtonine potentiates the antileukemic activity of arsenic trioxide against acute myeloid leukemia cells. 2019 Mar 15 2
3 31121982 NDRG2 Sensitizes Myeloid Leukemia to Arsenic Trioxide via GSK3β-NDRG2-PP2A Complex Formation. 2019 May 22 1
4 29959200 Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells. 2018 Sep 3
5 30213730 The suppressive effect of arsenic trioxide on TET2-FOXP3-Lyn-Akt axis-modulated MCL1 expression induces apoptosis in human leukemia cells. 2018 Nov 1 7
6 28024471 [Combination of Homoharringtonine with Arsenic Trioxide Induces Apoptosis of Human Acute Myeloid Leukemia Cell Line U937]. 2016 Dec 1
7 25758096 The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation. 2015 Jul 1
8 26540567 Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. 2015 Dec 29 5
9 22751450 Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells. 2013 Feb 6
10 23980369 [Homoharringtonine combined arsenic trioxide induced apoptosis in human multiple myeloma cell line RPMI 8226: an experimental research]. 2013 Jun 1
11 21473291 Arsenic trioxide induces apoptosis of Burkitt lymphoma cell lines through multiple apoptotic pathways and triggers antiangiogenesis. 2011 1
12 19549371 [Effect of arsenic trioxide on apoptosis in lymphoblastoid Raji cell line with relation to expression of mcl-1 gene]. 2009 Jun 2
13 18583568 Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways. 2008 Sep 15 2