Doxorubicin

MCL1 apoptosis regulator, BCL2 family member ; Homo sapiens







27 Article(s)
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1 35151832 PHLPP1 deficiency ameliorates cardiomyocyte death and cardiac dysfunction through inhibiting Mcl-1 degradation. 2022 Apr 2
2 33639139 Anti-CD19 mAb modified mesoporous titanium dioxide as exclusively targeting vector for efficient B-lymphoblastic leukemia therapy. 2021 Jul 1
3 33670870 Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling. 2021 Feb 28 1
4 34689155 Doxorubicin-induced novel circRNA_0004674 facilitates osteosarcoma progression and chemoresistance by upregulating MCL1 through miR-142-5p. 2021 Oct 23 1
5 32801295 Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance. 2020 Aug 15 1
6 30562553 Differential effects of protein kinase C-eta on apoptosis versus senescence. 2019 Mar 1
7 28947136 BCL-xL-selective BH3 mimetic sensitizes rhabdomyosarcoma cells to chemotherapeutics by activation of the mitochondrial pathway of apoptosis. 2018 Jan 1 1
8 30119255 Long noncoding RNA SNHG12 mediates doxorubicin resistance of osteosarcoma via miR-320a/MCL1 axis. 2018 Oct 2
9 30417787 Molecular Effects of Treatment of Human Colorectal Cancer Cells with Natural and Classical Chemotherapeutic Drugs: Alterations in the Expression of Apoptosis-related BCL2 Family Members, Including BCL2L12. 2018 1
10 28714472 Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy. 2017 Jul 17 1
11 26680268 A NOXA/MCL-1 Imbalance Underlies Chemoresistance of Malignant Rhabdoid Tumor Cells. 2016 Sep 2
12 26718267 MicroRNA-101 sensitizes hepatocellular carcinoma cells to doxorubicin-induced apoptosis via targeting Mcl-1. 2016 Feb 2
13 26892009 Sec6/8 regulates Bcl-2 and Mcl-1, but not Bcl-xl, in malignant peripheral nerve sheath tumor cells. 2016 May 2
14 25894378 The role of miR-125b-mitochondria-caspase-3 pathway in doxorubicin resistance and therapy in human breast cancer. 2015 Sep 2
15 26425662 Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage. 2015 1
16 26473375 JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis. 2015 Nov 10 1
17 26526790 miR-193b Modulates Resistance to Doxorubicin in Human Breast Cancer Cells by Downregulating MCL-1. 2015 4
18 24814395 Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA. 2014 Aug 28 1
19 22752851 Protective effect of plaunotol against doxorubicin-induced renal cell death. 2013 Apr 2
20 23449477 Polymeric delivery of siRNA for dual silencing of Mcl-1 and P-glycoprotein and apoptosis induction in drug-resistant breast cancer cells. 2013 Mar 3
21 22314265 Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines. 2012 Jul 1
22 22457358 α2β1 integrin promotes chemoresistance against doxorubicin in cancer cells through extracellular signal-regulated kinase (ERK). 2012 May 18 2
23 22581584 ADAM10 overexpression confers resistance to doxorubicin-induced apoptosis in hepatocellular carcinoma. 2012 Oct 1
24 20856197 PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis. 2011 Jan 27 2
25 17653083 A pivotal role for Mcl-1 in Bortezomib-induced apoptosis. 2008 Jan 31 1
26 18818206 Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. 2008 Nov 28 1
27 17147248 [Reversal of multi-drug resistance in K562/A02 cells by two short hairpin RNAs (shRNA) of mdr1]. 2006 Jul 4