Levodopa

tyrosine hydroxylase ; Rattus norvegicus







35 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30536670 Role of the HIF-1α/Nur77 axis in the regulation of the tyrosine hydroxylase expression by insulin in PC12 cells. 2019 Jul 2
2 31819070 Palm Fruit Bioactives augment expression of Tyrosine Hydroxylase in the Nile Grass Rat basal ganglia and alter the colonic microbiome. 2019 Dec 9 2
3 29452071 CaMKII inhibition ameliorated levodopa-induced dyskinesia by downregulating tyrosine hydroxylase activity in an experimental model of Parkinson's disease. 2018 May 15 1
4 28337120 Antidyskinetic Effects of MEK Inhibitor Are Associated with Multiple Neurochemical Alterations in the Striatum of Hemiparkinsonian Rats. 2017 1
5 28750831 Potential role of tyrosine hydroxylase in the loss of psychostimulant effect of amphetamine under conditions of impaired dopamine transporter activity. 2017 Sep 15 1
6 27173342 Effect of siRNA-induced silencing of cellular prion protein on tyrosine hydroxylase expression in the substantia nigra of a rat model of Parkinson's disease. 2016 May 9 2
7 23539311 Neurotoxic effects of berberine on long-term L-DOPA administration in 6-hydroxydopamine-lesioned rat model of Parkinson's disease. 2013 Jun 1
8 22242182 Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways. 2012 1
9 22293035 Modulatory effects of sesamin on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. 2012 Jun 1
10 21530574 Increased pain perception and attenuated opioid antinociception in paradoxical sleep-deprived rats are associated with reduced tyrosine hydroxylase staining in the periaqueductal gray matter and are reversed by L-dopa. 2011 Jul 1
11 21624436 The role of oxidative stress in neuromelanin synthesis in PC12 cells. 2011 Aug 25 1
12 19686242 Optimization of continuous in vivo DOPA production and studies on ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats. 2009 Oct 2
13 20037632 Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation. 2009 Dec 23 1
14 20411784 Distinct effects of intranigral L-DOPA infusion in the MPTP rat model of Parkinson's disease. 2009 1
15 17451064 Effect of local (intracerebral and intracerebroventricular) administration of tyrosine hydroxylase inhibitor on the neuroendocrine dopaminergic neurons and prolactin release. 2007 Mar 30 2
16 16182609 Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease. 2006 Jan 3
17 12358737 A site-specific mutation of tyrosine hydroxylase reduces feedback inhibition by dopamine in genetically modified cells grafted in parkinsonian rats. 2002 Oct 3
18 12377373 Inhibitory effects of tributyltin on dopamine biosynthesis in rat PC12 cells. 2002 Oct 25 4
19 11436352 Gene therapy for Parkinson's disease: determining the genes necessary for optimal dopamine replacement in rat models. 2001 Mar 2
20 10657530 Pituitary adenylate cyclase-activating polypeptide (PACAP-27) enhances tyrosine hydroxylase activity in the nucleus accumbens of the rat. 1999 Dec 1
21 9585350 Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions. 1998 May 1
22 9853519 Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors. 1998 Nov 20 1
23 8635567 Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: in vitro characterization and in vivo effects in the rat Parkinson model. 1996 May 1
24 8699255 Double transduction with GTP cyclohydrolase I and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts. 1996 Jul 15 1
25 7682705 A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase gene expression. 1993 Apr 15 2
26 8097025 Tyrosine hydroxylase immunoreactivity in cerebellar Purkinje cells of the rat. 1993 Feb 5 1
27 8097235 Short-term inhibitory effect of estradiol on tyrosine hydroxylase activity in tuberoinfundibular dopaminergic neurons in vitro. 1993 May 1
28 1672072 Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-dopa. 1991 Mar 2
29 1970430 Tetrahydrobiopterin-dependent production of L-dopa in NRK fibroblasts transfected with tyrosine hydroxylase cDNA: future use for intracerebral grafting. 1990 Feb 16 5
30 2570369 Mass and in situ molar activity of tyrosine hydroxylase in the median eminence. Effect of thyroidectomy and thyroid hormone replacement. 1989 Jun 2
31 2896121 Mass and in situ activity of tyrosine hydroxylase in the median eminence: effect of hyperprolactinemia. 1988 May 4
32 2897232 Saline ingestion stimulates the in situ molar activity of tyrosine hydroxylase in the median eminence and superior cervical ganglion. 1988 Apr 19 4
33 2907999 Mass and activity of tyrosine hydroxylase in tuberoinfundibular dopaminergic neurons of the aged brain. Control by prolactin and ovarian hormones. 1988 Dec 2
34 2872094 In situ activity and phosphorylation of tyrosine hydroxylase in the median eminence. 1986 Jun 3
35 2879287 Hormonal modulation of the quantity and in situ activity of tyrosine hydroxylase in neurites of the median eminence. 1986 Dec 1