Title : Increased pain perception and attenuated opioid antinociception in paradoxical sleep-deprived rats are associated with reduced tyrosine hydroxylase staining in the periaqueductal gray matter and are reversed by L-dopa.

Pub. Date : 2011 Jul

PMID : 21530574






1 Functional Relationships(s)
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1 In conclusion, increased thermal sensitivity was reversed by L-DOPA and could be caused by a reduction TH levels in the PAG. Levodopa tyrosine hydroxylase Rattus norvegicus