Oxidopamine

tyrosine hydroxylase ; Rattus norvegicus







74 Article(s)
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1 32441169 The effect of chronic neuropeptide-S treatment on non-motor parameters in experimental model of Parkinson's disease. 2021 Aug 1
2 34512945 Neuroprotective Effect of Intrastriatal Caffeic Acid Phenethyl Ester Treatment in 6-OH Dopamine Model of Parkinson's Disease in Rats. 2021 1
3 27844282 Morphological Changes in a Severe Model of Parkinson's Disease and Its Suitability to Test the Therapeutic Effects of Microencapsulated Neurotrophic Factors. 2017 Dec 1
4 27915043 Involvement of BDNF/TrkB signaling in the effect of diphenyl diselenide on motor function in a Parkinson's disease rat model. 2017 Jan 15 2
5 28247332 Intranasal Administration of GDNF Protects Against Neural Apoptosis in a Rat Model of Parkinson's Disease Through PI3K/Akt/GSK3β Pathway. 2017 May 1
6 28504195 FGF18 protects against 6-hydroxydopamine-induced nigrostriatal damage in a rat model of Parkinson's disease. 2017 Jul 25 3
7 28611572 4R-Cembranoid Improves Outcomes after 6-Hydroxydopamine Challenge in Both In vitro and In vivo Models of Parkinson's Disease. 2017 1
8 28004763 Tyrosine Hydroxylase Binding to Phospholipid Membranes Prompts Its Amyloid Aggregation and Compromises Bilayer Integrity. 2016 Dec 22 1
9 25999268 Methodology and effects of repeated intranasal delivery of DNSP-11 in a rat model of Parkinson's disease. 2015 Aug 15 2
10 24297323 Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson's model. 2014 Jun 4
11 24462728 High frequency stimulation of subthalamic nucleus results in behavioral recovery by increasing striatal dopamine release in 6-hydroxydopamine lesioned rat. 2014 Apr 15 1
12 25230286 Intraventricular injection of 6-hydroxydopamine results in an increased number of tyrosine hydroxylase immune-positive cells in the rat cortex. 2014 Nov 7 2
13 23018122 Differential sensitivity of cranial and limb motor function to nigrostriatal dopamine depletion. 2013 Jan 15 1
14 23279934 Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses. 2013 Mar 3
15 23539311 Neurotoxic effects of berberine on long-term L-DOPA administration in 6-hydroxydopamine-lesioned rat model of Parkinson's disease. 2013 Jun 3
16 23652161 Neuroprotective and behavioural assessments of an imidazolium compound (DBZIM) in a rat model of Parkinson's disease induced by 6-OHDA. 2013 Sep 5 1
17 23714698 Catechin attenuates behavioral neurotoxicity induced by 6-OHDA in rats. 2013 Sep 1
18 23868341 Dynamic expressions of Beclin 1 and tyrosine hydroxylase in different areas of 6-hydroxydopamine-induced Parkinsonian rats. 2013 Oct 3
19 22048886 Ether-à-go-go 1 (Eag1) potassium channel expression in dopaminergic neurons of basal ganglia is modulated by 6-hydroxydopamine lesion. 2012 Apr 1
20 22622825 Curcumin protects nigral dopaminergic neurons by iron-chelation in the 6-hydroxydopamine rat model of Parkinson's disease. 2012 Jun 1
21 22842585 Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats. 2012 Sep 18 1
22 22850559 A novel use of combined tyrosine hydroxylase and silver nucleolar staining to determine the effects of a unilateral intrastriatal 6-hydroxydopamine lesion in the substantia nigra: a stereological study. 2012 Sep 30 1
23 20570658 Efficacy of Tyrosine Hydroxylase gene modified neural stem cells derived from bone marrow on Parkinson's disease--a rat model study. 2010 Jul 30 2
24 18816795 1,25-Dihydroxyvitamin D3 administration to 6-hydroxydopamine-lesioned rats increases glial cell line-derived neurotrophic factor and partially restores tyrosine hydroxylase expression in substantia nigra and striatum. 2009 Feb 15 5
25 19844994 The dual dopamine-glutamate phenotype of growing mesencephalic neurons regresses in mature rat brain. 2009 Dec 20 1
26 18042492 Glutamate in dopamine neurons: synaptic versus diffuse transmission. 2008 Aug 4
27 18420351 Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease. 2008 May 15 2
28 18430361 Bilobalide inhibits 6-OHDA-induced activation of NF-kappaB and loss of dopaminergic neurons in rat substantia nigra. 2008 May 1
29 18706980 Enhanced glutamatergic phenotype of mesencephalic dopamine neurons after neonatal 6-hydroxydopamine lesion. 2008 Sep 22 2
30 17914186 Reversible unilateral nigrostriatal pathway inhibition induced through expression of adenovirus-mediated clostridial light chain gene in the substantia nigra. 2007 1
31 15717064 Tyrosine hydroxylase replacement in experimental Parkinson's disease with transvascular gene therapy. 2005 Jan 3
32 16298737 Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. 2005 Oct 1
33 14689453 Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions. 2004 Jan 1 3
34 14696016 Lesion of subthalamic or motor thalamic nucleus in 6-hydroxydopamine-treated rats: effects on striatal glutamate and apomorphine-induced contralateral rotations. 2004 Mar 15 4
35 15053859 Normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism with intravenous nonviral gene therapy and a brain-specific promoter. 2004 Apr 1
36 15142343 The antioxidant drink effective microorganism-X (EM-X) pre-treatment attenuates the loss of nigrostriatal dopaminergic neurons in 6-hydroxydopamine-lesion rat model of Parkinson's disease. 2004 May 1
37 15246853 Quantitative analyses of GFRalpha-1 and GFRalpha-2 mRNAs and tyrosine hydroxylase protein in the nigrostriatal system reveal bilateral compensatory changes following unilateral 6-OHDA lesions in the rat. 2004 Aug 6 1
38 12691607 Correction of a rat model of Parkinson's disease by coexpression of tyrosine hydroxylase and aromatic amino acid decarboxylase from a helper virus-free herpes simplex virus type 1 vector. 2003 Mar 20 5
39 12965246 Failure of estrogen to protect the substantia nigra pars compacta of female rats from lesion induced by 6-hydroxydopamine. 2003 Oct 3 2
40 14673496 Long term gene therapy of Parkinson's disease using immortalized rat glial cell line with tyrosine hydroxylase gene. 2003 Dec 4
41 11983283 Induction of tyrosine hydroxylase expression in rat fetal striatal precursor cells following transplantation. 2002 May 10 1
42 12165403 Neuroprotective effect of the monoamine oxidase inhibitor PF 9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] on rat nigral neurons after 6-hydroxydopamine-striatal lesion. 2002 Aug 30 2
43 12176170 Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease. 2002 Aug 30 1
44 12658754 Experimental study on heterograft of glomus cells of carotid body for hemiparkinsonian rats. 2002 1
45 11241387 Comparison of unilateral and bilateral intrastriatal 6-hydroxydopamine-induced axon terminal lesions: evidence for interhemispheric functional coupling of the two nigrostriatal pathways. 2001 Apr 2 1
46 10694827 Long-term phenotypic correction of rodent hemiparkinsonism by gene therapy using genetically modified myoblasts. 2000 Mar 1
47 10719076 N-terminal tripeptide of IGF-1 (GPE) prevents the loss of TH positive neurons after 6-OHDA induced nigral lesion in rats. 2000 Mar 24 1
48 10865059 On the altered expression of tyrosine hydroxylase and calbindin-D 28kD immunoreactivities and viability of neurons in the ventral tegmental area of Tsai following injections of 6-hydroxydopamine in the medial forebrain bundle in the rat. 2000 Jun 30 1
49 10945765 Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease. 2000 Jul 20 1
50 9973233 Differential effects of chemical sympathectomy on expression and activity of tyrosine hydroxylase and levels of catecholamines and DOPA in peripheral tissues of rats. 1999 Jan 3