| 1 |
35153796 | Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling Pathways. | 2022 |
1 |
| 2 |
34012468 | Expression Profile of Long Noncoding RNAs and Circular RNAs in Mouse C3H10T1/2 Mesenchymal Stem Cells Undergoing Myogenic and Cardiomyogenic Differentiation. | 2021 |
1 |
| 3 |
32380342 | Design, synthesis and biological evaluation of pyridine derivatives as selective SHP2 inhibitors. | 2020 Jul |
1 |
| 4 |
29786073 | Integrin α6β4-Src-AKT signaling induces cellular senescence by counteracting apoptosis in irradiated tumor cells and tissues. | 2019 Jan |
1 |
| 5 |
30667096 | The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice. | 2019 May |
1 |
| 6 |
28237515 | AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia. | 2017 May |
1 |
| 7 |
29144234 | LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. | 2017 Nov 16 |
1 |
| 8 |
29229986 | High-fat diet-induced obesity impairs insulin signaling in lungs of allergen-challenged mice: Improvement by resveratrol. | 2017 Dec 11 |
1 |
| 9 |
26328540 | Combination of PKCε Activation and PTP1B Inhibition Effectively Suppresses Aβ-Induced GSK-3β Activation and Tau Phosphorylation. | 2016 Sep |
2 |
| 10 |
24837366 | The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner. | 2015 Mar 26 |
1 |
| 11 |
23275337 | Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells. | 2013 Feb 22 |
1 |
| 12 |
23778885 | Phosphorylation of cMet tyrosine residues in murine ascitic hepatic cancer cell lines with different lymph node metastatic potentials. | 2013 Aug |
1 |
| 13 |
23973607 | Astrocytic phosphorylation of PDK1 on Tyr9 following an excitotoxic lesion in the mouse hippocampus. | 2013 Oct 2 |
1 |
| 14 |
22543210 | Recovery from radiation-induced bone marrow damage by HSP25 through Tie2 signaling. | 2012 Sep 1 |
1 |
| 15 |
21255641 | Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation. | 2011 May |
1 |
| 16 |
21900501 | The SHP-1 protein tyrosine phosphatase negatively modulates Akt signaling in the ghrelin/GHSR1a system. | 2011 Nov |
1 |
| 17 |
19852956 | Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration. | 2010 Mar 10 |
2 |
| 18 |
20004975 | Insulin potentiates FcepsilonRI-mediated signaling in mouse bone marrow-derived mast cells. | 2010 Feb |
1 |
| 19 |
20061388 | Enhanced retinal insulin receptor-activated neuroprotective survival signal in mice lacking the protein-tyrosine phosphatase-1B gene. | 2010 Mar 19 |
1 |
| 20 |
20103705 | Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: potential role of tyrosine nitration of insulin signaling proteins. | 2010 Apr |
4 |
| 21 |
20133944 | c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway. | 2010 Apr 2 |
2 |
| 22 |
20333297 | Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. | 2010 Mar 19 |
2 |
| 23 |
20606012 | Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor. | 2010 Sep |
4 |
| 24 |
18805968 | Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. | 2009 Jan 8 |
1 |
| 25 |
19398586 | Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation. | 2009 Jul |
3 |
| 26 |
19541746 | Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis. | 2009 Sep |
1 |
| 27 |
18209096 | Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis. | 2008 Feb 1 |
1 |
| 28 |
18421086 | PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells. | 2008 Aug |
1 |
| 29 |
18480052 | Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells. | 2008 Jul 11 |
1 |
| 30 |
17971444 | Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2: implications for cellular morphology. | 2007 Dec 28 |
1 |
| 31 |
15982852 | Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression. | 2006 Feb |
1 |
| 32 |
16157472 | PI 3 kinase-dependent Akt kinase and PKCepsilon independently regulate interferon-gamma-induced STAT1alpha serine phosphorylation to induce monocyte chemotactic protein-1 expression. | 2006 Apr |
1 |
| 33 |
16782882 | Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine. | 2006 Jul |
3 |
| 34 |
15657136 | Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation. | 2005 Jan 25 |
2 |
| 35 |
15964830 | Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia. | 2005 Jul |
1 |
| 36 |
15988755 | Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells. | 2005 Oct 1 |
1 |
| 37 |
14656892 | G-CSF-induced tyrosine phosphorylation of Gab2 is Lyn kinase dependent and associated with enhanced Akt and differentiative, not proliferative, responses. | 2004 May 1 |
2 |
| 38 |
15340065 | A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia. | 2004 Sep |
1 |
| 39 |
15500006 | Screening for small molecule inhibitors of insulin-like growth factor receptor (IGF-1R) kinase: comparison of homogeneous time-resolved fluorescence and 33P-ATP plate assay formats. | 2004 Jul |
1 |
| 40 |
15550174 | The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway. | 2004 Nov 18 |
1 |
| 41 |
14559149 | Tyrosine phosphorylation of Disabled-1 is essential for Reelin-stimulated activation of Akt and Src family kinases. | 2003 Oct 7 |
2 |
| 42 |
12483539 | A role for SHPS-1/SIRPalpha1 in IL-1beta- and TNFalpha-dependent signaling. | 2002 Dec 12 |
1 |
| 43 |
11445557 | Regulation of Akt/PKB activation by tyrosine phosphorylation. | 2001 Aug 24 |
2 |
| 44 |
11453660 | Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite. | 2001 Jul 20 |
1 |
| 45 |
10766839 | A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt. | 2000 Apr 21 |
1 |
| 46 |
11018758 | Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice. | 2000 Oct |
1 |
| 47 |
10224144 | FcgammaRIIb modulation of surface immunoglobulin-induced Akt activation in murine B cells. | 1999 May 7 |
1 |