| 1 |
34427916 | Metformin accelerates wound healing by Akt phosphorylation of gingival fibroblasts in insulin-resistant prediabetes mice. | 2022 Feb |
1 |
| 2 |
34597809 | Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models. | 2022 Mar |
1 |
| 3 |
34678341 | Effects of oral administration of polystyrene nanoplastics on plasma glucose metabolism in mice. | 2022 Feb |
1 |
| 4 |
35104662 | Vinexin β deficiency exacerbates diet-induced obesity, hepatosteatosis, insulin resistance and endoplasmic reticulum stress in mice. | 2022 Mar 12 |
1 |
| 5 |
35126394 | Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions. | 2022 |
1 |
| 6 |
35129868 | Resolvin E3 ameliorates high-fat diet-induced insulin resistance via the phosphatidylinositol-3-kinase/Akt signaling pathway in adipocytes. | 2022 Mar |
1 |
| 7 |
35192202 | A novel natural PPARγ agonist, Gypenoside LXXV, ameliorates cognitive deficits by enhancing brain glucose uptake via the activation of Akt/GLUT4 signaling in db/db mice. | 2022 Apr |
1 |
| 8 |
35275401 | Hypoglycemic and hypolipidemic effects of polysaccharide isolated from Sphacelotheca sorghi in diet-streptozotocin-induced T2D mice. | 2022 Apr |
1 |
| 9 |
35447553 | Korean naked waxy barley (saechalssal) extract reduces blood glucose in diabetic mice by modulating the PI3K-Akt-GSK3β pathway. | 2022 Jun |
1 |
| 10 |
35502441 | 2'-O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway. | 2022 |
1 |
| 11 |
32749748 | Aurantio-obtusin improves obesity and insulin resistance induced by high-fat diet in obese mice. | 2021 Jan |
1 |
| 12 |
32816106 | YAP mediates the interaction between the Hippo and PI3K/Akt pathways in mesangial cell proliferation in diabetic nephropathy. | 2021 Jan |
1 |
| 13 |
32942336 | Clusterin suppresses spermatogenic cell apoptosis to alleviate diabetes-induced testicular damage by inhibiting autophagy via the PI3K/AKT/mTOR axis. | 2021 Jan |
1 |
| 14 |
33295913 | High n-3 fatty acids counteract hyperglycemia-induced insulin resistance in fat-1 mice via pre-adipocyte NLRP3 inflammasome inhibition. | 2021 Jan 7 |
1 |
| 15 |
33337347 | Hypothalamic BMP9 suppresses glucose production by central PI3K/Akt/mTOR pathway. | 2021 Feb |
1 |
| 16 |
33414476 | METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial-mesenchymal transition of renal tubular cells in diabetic kidney disease. | 2021 Jan 4 |
3 |
| 17 |
33516878 | Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation. | 2021 Mar 12 |
1 |
| 18 |
33537812 | FBXW7 mediates high glucose‑induced SREBP‑1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation. | 2021 Apr |
3 |
| 19 |
33613705 | 4-Methoxybenzylalcohol protects brain microvascular endothelial cells against oxygen-glucose deprivation/reperfusion-induced injury via activation of the PI3K/AKT signaling pathway. | 2021 Mar |
1 |
| 20 |
33647469 | Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice. | 2021 Jul |
1 |
| 21 |
33660027 | Lithium enhances exercise-induced glycogen breakdown and insulin-induced AKT activation to facilitate glucose uptake in rodent skeletal muscle. | 2021 Apr |
1 |
| 22 |
33715230 | ATM inhibitor KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake in aggressive cancer cells with sustained activation of Akt. | 2021 Apr |
2 |
| 23 |
33788626 | Cassia Abbreviata Enhances Glucose Uptake and Glucose Transporter 4 Translocation in C2C12 Mouse Skeletal Muscle Cells. | 2021 Jan-Dec |
1 |
| 24 |
33794128 | Pueraria lobata root polysaccharide alleviates glucose and lipid metabolic dysfunction in diabetic db/db mice. | 2021 Dec |
1 |
| 25 |
33795530 | Photobiomodulation therapy ameliorates hyperglycemia and insulin resistance by activating cytochrome c oxidase-mediated protein kinase B in muscle. | 2021 Mar 26 |
2 |
| 26 |
33799458 | Phloridzin Acts as an Inhibitor of Protein-Tyrosine Phosphatase MEG2 Relevant to Insulin Resistance. | 2021 Mar 14 |
1 |
| 27 |
33809508 | Doxepin Exacerbates Renal Damage, Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Urinary Chromium Loss in Obese Mice. | 2021 Mar 16 |
1 |
| 28 |
33896390 | Low glucose and serum levels cause an increased inflammatory factor in 3T3-L1 cell through Akt, MAPKs and NF-кB activation. | 2021 Dec |
3 |
| 29 |
33906607 | Uncarboxylated osteocalcin alleviates the inhibitory effect of high glucose on osteogenic differentiation of mouse bone marrow-derived mesenchymal stem cells by regulating TP63. | 2021 Apr 27 |
1 |
| 30 |
33999329 | Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. | 2021 Oct |
1 |
| 31 |
34025589 | Mouse Spexin: (III) Differential Regulation by Glucose and Insulin in Glandular Stomach and Functional Implication in Feeding Control. | 2021 |
1 |
| 32 |
34053181 | Cardiac metallothionein overexpression rescues diabetic cardiomyopathy in Akt2-knockout mice. | 2021 Jul |
1 |
| 33 |
34162834 | TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression. | 2021 Jun 23 |
1 |
| 34 |
34299508 | Exploration of Hypoglycemic Activity of Saccharomyces pastorianus Extract and Evaluation of the Molecular Mechanisms. | 2021 Jul 12 |
2 |
| 35 |
34314059 | Biglycan reduces body weight by regulating food intake in mice and improves glucose metabolism through AMPK/AKT dual pathways in skeletal muscle. | 2021 Aug |
1 |
| 36 |
34331233 | Mutant Huntingtin Impairs Pancreatic β-cells by Recruiting IRS-2 and Disturbing the PI3K/AKT/FoxO1 Signaling Pathway in Huntington's Disease. | 2021 Dec |
2 |
| 37 |
34341463 | Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes. | 2021 Aug 2 |
1 |
| 38 |
34691353 | Kudzu Resistant Starch: An Effective Regulator of Type 2 Diabetes Mellitus. | 2021 |
1 |
| 39 |
34724097 | Role of Akt isoforms in neuronal insulin signaling and resistance. | 2021 Dec |
5 |
| 40 |
34766133 | Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus. | 2021 Mar |
1 |
| 41 |
34863080 | The isoflavone puerarin exerts anti-tumor activity in pancreatic ductal adenocarcinoma by suppressing mTOR-mediated glucose metabolism. | 2021 Dec 4 |
1 |
| 42 |
34952629 | Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway. | 2021 Dec 24 |
2 |
| 43 |
31680298 | LncRNA-XIST/microRNA-126 sponge mediates cell proliferation and glucose metabolism through the IRS1/PI3K/Akt pathway in glioma. | 2020 Mar |
1 |
| 44 |
31735337 | PICK1 attenuates high glucose-induced pancreatic β-cell death through the PI3K/Akt pathway and is negatively regulated by miR-139-5p. | 2020 Jan 29 |
1 |
| 45 |
31887379 | Exopolysaccharides of Bacillus amyloliquefaciens modulate glycemic level in mice and promote glucose uptake of cells through the activation of Akt. | 2020 Mar 1 |
2 |
| 46 |
32133736 | USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation. | 2020 Apr 3 |
1 |
| 47 |
32148419 | The non-saponin fraction of Korean Red Ginseng (KGC05P0) decreases glucose uptake and transport in vitro and modulates glucose production via down-regulation of the PI3K/AKT pathway in vivo. | 2020 Mar |
1 |
| 48 |
32197570 | Bound Phenolics Ensure the Antihyperglycemic Effect of Rice Bran Dietary Fiber in db/db Mice via Activating the Insulin Signaling Pathway in Skeletal Muscle and Altering Gut Microbiota. | 2020 Apr 15 |
1 |
| 49 |
32271168 | Soluble (pro)renin receptor treats metabolic syndrome in mice with diet-induced obesity via interaction with PPARγ. | 2020 Apr 9 |
1 |
| 50 |
32325423 | SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion. | 2020 Jul |
1 |