Title : METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial-mesenchymal transition of renal tubular cells in diabetic kidney disease.

Pub. Date : 2021 Jan 4

PMID : 33414476






3 Functional Relationships(s)
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1 Furthermore, HDAC5 expression was regulated by PI3K/Akt signaling pathway and inhibition of PI3K/Akt pathway by LY294002 treatment or Akt phosphorylation mutation reduced HDAC5 and TGF-beta1 expression in vitro high glucose-cultured HK2 cells. Glucose thymoma viral proto-oncogene 1 Mus musculus
2 Furthermore, HDAC5 expression was regulated by PI3K/Akt signaling pathway and inhibition of PI3K/Akt pathway by LY294002 treatment or Akt phosphorylation mutation reduced HDAC5 and TGF-beta1 expression in vitro high glucose-cultured HK2 cells. Glucose thymoma viral proto-oncogene 1 Mus musculus
3 Furthermore, HDAC5 expression was regulated by PI3K/Akt signaling pathway and inhibition of PI3K/Akt pathway by LY294002 treatment or Akt phosphorylation mutation reduced HDAC5 and TGF-beta1 expression in vitro high glucose-cultured HK2 cells. Glucose thymoma viral proto-oncogene 1 Mus musculus