Methadone

cytochrome P450 family 2 subfamily C member 19 ; Homo sapiens







17 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32841585 Pharmacogenomics biomarkers for personalized methadone maintenance treatment: The mechanism and its potential use. 2021 Apr 1 3
2 32444381 Clinically Significant Drug-Drug Interaction Between Methadone and Cannabidiol. 2020 Jun 1
3 30205091 Methadone Metabolism and Drug-Drug Interactions: In Vitro and In Vivo Literature Review. 2018 Dec 1
4 27199033 Effects of CYP2C19 variants on methadone metabolism in vitro. 2017 Apr 3
5 28723731 Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment. 2017 Oct 1
6 27386066 "Influence of methadone on clopidogrel in addicts on methadone maintenance therapy" Drug interaction between methadone and clopidogrel. 2016 Spring 1
7 25903311 A Possible Mechanistic Link Between the CYP2C19 Genotype, the Methadone Metabolite Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidene (EDDP), and Methadone-Induced Corrected QT Interval Prolongation in a Pilot Study. 2015 Apr 2
8 24956251 Assessment of CYP450 genetic variability effect on methadone dose and tolerance. 2014 May 3
9 24016178 Functional genetic polymorphisms in CYP2C19 gene in relation to cardiac side effects and treatment dose in a methadone maintenance cohort. 2013 Oct 6
10 25278738 Pharmacogenomics study in a Taiwan methadone maintenance cohort. 2013 Dec 2
11 19904716 Development of a method to measure methadone enantiomers and its metabolites without enantiomer standard compounds for the plasma of methadone maintenance patients. 2010 Jul 2
12 17259447 Enantiomeric metabolic interactions and stereoselective human methadone metabolism. 2007 Apr 2
13 17598095 An in vitro approach to potential methadone metabolic-inhibition interactions. 2007 Sep 1
14 16338275 Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment. 2005 Dec 2
15 14628297 Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. 2004 Jan 1
16 12900870 Capillary electrophoresis to assess drug metabolism induced in vitro using single CYP450 enzymes (Supersomes): application to the chiral metabolism of mephenytoin and methadone. 2003 Aug 2
17 10233205 Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4. 1999 Apr 1