Eflornithine

ornithine decarboxylase, structural 1 ; Mus musculus







230 Article(s)
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51 12873989 Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis. 2003 Jul 15 1
52 14568000 Elevated levels of polyamines alter chromatin in murine skin and tumors without global changes in nucleosome acetylation. 2003 Nov 1 2
53 11782361 Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors. 2002 Jan 1 2
54 11853879 Regulation of ornithine decarboxylase in B16 mouse melanoma cells: synergistic activation of melanogenesis by alphaMSH and ornithine decarboxylase inhibition. 2002 Jan 30 2
55 11888902 Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice. 2002 Mar 1 2
56 12054570 The preovulatory rise of ovarian ornithine decarboxylase is required for progesterone secretion by the corpus luteum. 2002 Apr 26 4
57 12220664 Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion. 2002 Sep 11 3
58 12441138 Putrescine activates oxidative stress dependent apoptotic death in ornithine decarboxylase overproducing mouse myeloma cells. 2002 Nov 15 1
59 11160858 Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs. 2001 Feb 1
60 11549581 A definitive role of ornithine decarboxylase in photocarcinogenesis. 2001 Sep 1
61 10728361 Central role for ornithine decarboxylase in beta-adrenoceptor mediated hypertrophy. 2000 Jan 14 1
62 10782045 Prolactin stimulation of iodide uptake and incorporation into protein is polyamine-dependent in mouse mammary gland explants. 2000 May 1
63 10903418 Inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin ornithine decarboxylase and protein kinase C by polyphenolics from grapes. 2000 Jun 15 2
64 11016639 Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice. 2000 Sep 15 3
65 11059762 Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice. 2000 Oct 15 5
66 11128555 Inhibition of ornithine decarboxylase by alpha-difluoromethylornithine induces apoptosis of HC11 mouse mammary epithelial cells. 2000 2
67 11142412 Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithine. 2000 Dec 1
68 10353628 Early alterations of polyamine metabolism induced after acute administration of clenbuterol in mouse heart. 1999 2
69 10393094 p44/42 mitogen-activated protein kinase is involved in the expression of ornithine decarboxylase in leukaemia L1210 cells. 1999 Jul 15 2
70 10433086 Polyamine-fas interactions: inhibition of polyamine biosynthesis in MRL-lpr/lpr mice is associated with the up-regulation of fas mRNA in thymocytes. 1999 4
71 10446971 Difluoromethylornithine chemoprevention of epidermal carcinogenesis in K14-HPV16 transgenic mice. 1999 Aug 1 3
72 10469614 APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse. 1999 Sep 3
73 10563800 X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine. 1999 Nov 16 3
74 10607308 alpha-Difluoromethylornithine blocks thymocyte apoptosis via a reduction in tyrosine phosphorylation. 1999 Dec 1
75 10728786 D,L-alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, induces differentiation in MEL cells. 1999 5
76 9580224 Polyamine-mediated heart hypertrophy induced by clenbuterol in the mouse. 1998 Jan 1
77 9615732 Effects of suramin on polyamine metabolism in B16 murine melanoma cells. 1998 Mar-Apr 1
78 9615733 Opposing effects of suramin and DL-alpha-difluoromethylornithine on polyamine metabolism contribute to a synergistic action on B16 melanoma cell growth in vitro. 1998 Mar-Apr 1
79 9744537 Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. 1998 Aug 6
80 9769382 Inhibition of breast cancer in nude mouse model by anti-angiogenesis. 1998 Nov-Dec 4
81 9841492 Ornithine decarboxylase along the mouse and rat nephron. 1998 Jun 3
82 9884080 Inhibition of ornithine decarboxylase potentiates nitric oxide production in LPS-activated J774 cells. 1998 Dec 5
83 9020157 Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion. 1997 Feb 14 1
84 9139705 Ornithine decarboxylase expression leads to translocation and activation of protein kinase CK2 in vivo. 1997 May 9 1
85 9194572 Catecholamines are required for androgen-induced ODC expression but not for hypertrophy of mouse kidney. 1997 May 27 1
86 9210401 Inhibition of the expression of ornithine decarboxylase and c-Myc by cell-permeant ceramide in difluoromethylornithine-resistant leukaemia cells. 1997 Jun 15 3
87 9224728 Inhibition by 1alpha,25-dihydroxyvitamin D3 of activin A-induced differentiation of murine erythroleukemic F5-5 cells. 1997 Jul 15 4
88 9367837 Phosphatidylinositol 3-kinase is required for the induction of ornithine decarboxylase in leukemia cells stimulated to growth. 1997 Oct 29 2
89 8618048 Modulation of murine hair follicle function by alterations in ornithine decarboxylase activity. 1996 May 2
90 8664348 Inhibition of the expression of ornithine decarboxylase by some kappa-opioidergic receptor ligands in difluoromethylornithine-resistant L1210 cells. 1996 May 28 1
91 8937449 Inhibition of the expression of ornithine decarboxylase by haloperidol in difluoromethylornithine-resistant leukemia cells. 1996 Nov 8 3
92 9022291 Phorbol ester (12-O-tetradecanoylphorbol 13-acetate) prevents ornithine decarboxylase inhibition and apoptosis and L1210 leukemic cells exposed to TGF-beta 1. 1996 Dec 1
93 7474658 An evaluation of the role of polyamines in different models of kidney hypertrophy in mice. 1995 Sep 4
94 7780833 Arginine and ornithine metabolizing enzymes in testosterone-induced hypertrophic mouse kidney. 1995 Mar 1
95 7578852 Regulation of ornithine decarboxylase in the kidney of autoimmune mice with the lpr gene. 1994 3
96 7616752 Preclinical efficacy evaluation of potential chemopreventive agents in animal carcinogenesis models: methods and results from the NCI Chemoprevention Drug Development Program. 1994 1
97 7935984 The role of alpha-difluoromethyl ornithine as an adjuvant to immunotherapy in mice bearing transplantable tumors. 1994 4
98 7980394 The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine. 1994 Oct 15 1
99 8065308 Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis. 1994 Sep 4
100 8074711 Antizyme delays the restoration by spermine of growth of polyamine-deficient cells through its negative regulation of polyamine transport. 1994 Aug 30 5