Title : Antizyme delays the restoration by spermine of growth of polyamine-deficient cells through its negative regulation of polyamine transport.

Pub. Date : 1994 Aug 30

PMID : 8074711






5 Functional Relationships(s)
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1 Treatments of the transfected cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC), and dexamethasone, an inducer of antizyme, both caused a decrease in ODC activity and polyamine contents and inhibition of cell growth. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
2 Treatments of the transfected cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC), and dexamethasone, an inducer of antizyme, both caused a decrease in ODC activity and polyamine contents and inhibition of cell growth. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
3 Treatments of the transfected cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC), and dexamethasone, an inducer of antizyme, both caused a decrease in ODC activity and polyamine contents and inhibition of cell growth. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
4 Treatments of the transfected cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC), and dexamethasone, an inducer of antizyme, both caused a decrease in ODC activity and polyamine contents and inhibition of cell growth. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
5 Treatments of the transfected cells with alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase (ODC), and dexamethasone, an inducer of antizyme, both caused a decrease in ODC activity and polyamine contents and inhibition of cell growth. Eflornithine ornithine decarboxylase, structural 1 Mus musculus