Cholesterol

3-hydroxy-3-methylglutaryl-coenzyme A reductase ; Cricetulus griseus







16 Article(s)
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Pub. Year
#Total Relationships
1 33240873 Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis. 2020 3
2 29374057 Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase. 2018 Mar 16 2
3 17090658 Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation. 2007 Feb 1
4 10946023 In nonhepatic cells, cholesterol 7alpha-hydroxylase induces the expression of genes regulating cholesterol biosynthesis, efflux, and homeostasis. 2000 Aug 1
5 7844177 The regulated degradation of a 3-hydroxy-3-methylglutaryl-coenzyme A reductase reporter construct occurs in the endoplasmic reticulum. 1994 Sep 1
6 8102788 Loss of transcriptional activation of three sterol-regulated genes in mutant hamster cells. 1993 Sep 1
7 1606178 Increased cholesterol synthesis in Chinese hamster ovary cells deficient in peroxisomes. 1992 Jun 5 1
8 1906466 Inhibition of degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo by cysteine protease inhibitors. 1991 Jul 15 1
9 3624255 Modulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by azole antimycotics requires lanosterol demethylation, but not 24,25-epoxylanosterol formation. 1987 Sep 5 1
10 3995584 Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme. 1985 May 1
11 6705048 Increase in membrane cholesterol: a possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells. 1984 Apr 2
12 6643457 Mutant clone of Chinese hamster ovary cells lacking 3-hydroxy-3 -methylglutaryl coenzyme A reductase. 1983 Nov 25 3
13 6685129 Ultrastructural analysis of crystalloid endoplasmic reticulum in UT-1 cells and its disappearance in response to cholesterol. 1983 Sep 1
14 6951166 Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1982 Feb 1
15 7126620 Inhibition of protein synthesis blocks the response to 25-hydroxycholesterol by inhibiting degradation of hydroxymethylglutaryl-CoA reductase. 1982 Sep 14 1
16 7240242 Isolation and characterization of cells resistant to ML236B (compactin) with increased levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1981 Jul 10 1