Fatty Acids

stearoyl-CoA desaturase ; Homo sapiens







151 Article(s)
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1 34287816 Exosome-mediated delivery of SCD-1 siRNA promoted the death of anaplastic thyroid carcinoma cells via regulating ROS level. 2022 Feb 3
2 34997498 The dysregulation of unsaturated fatty acid-based metabolomics in the MNNG-induced malignant transformation of Het-1A cells. 2022 Apr 2
3 35046108 Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation. 2022 May 4 2
4 35126846 Stearoyl-CoA desaturase 1: A potential target for non-alcoholic fatty liver disease?-perspective on emerging experimental evidence. 2022 Jan 27 2
5 35173454 SCD1-Fatty Acid Desaturase Inhibitor MF-438 Alleviates Latent Inflammation Induced by Preservative-Free Prostaglandin Analog Eye Drops. 2022 1
6 35276817 Association between FADS Gene Expression and Polyunsaturated Fatty Acids in Breast Milk. 2022 Jan 20 2
7 35361481 Roles of miR-124-3p/Scd1 in urolithin A-induced brown adipocyte differentiation and succinate-dependent regulation of mitochondrial complex II. 2022 May 28 2
8 35533489 DDX17 protects hepatocytes against oleic acid/palmitic acid-induced lipid accumulation. 2022 Jul 5 1
9 35609330 Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells. 2022 May 2
10 32767911 The Correlation between Lipid Metabolism Disorders and Prostate Cancer. 2021 1
11 33049404 Stearoyl-CoA desaturase 5 (SCD5), a Δ-9 fatty acyl desaturase in search of a function. 2021 Jan 9
12 33218679 Lipid metabolism in colon cancer: Role of Liver X Receptor (LXR) and Stearoyl-CoA Desaturase 1 (SCD1). 2021 Apr 3
13 33612070 NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis. 2021 Feb 1 1
14 33628242 The Role of Dyslipidemia in Colitis-Associated Colorectal Cancer. 2021 1
15 34030117 Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence. 2021 Jul 1
16 34171462 Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding. 2021 Aug 6
17 34293334 Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis. 2021 Oct 7 2
18 34486791 Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids. 2021 Dec 2
19 34674740 A small molecule modulating monounsaturated fatty acids and Wnt signaling confers maintenance to induced pluripotent stem cells against endodermal differentiation. 2021 Oct 21 2
20 34680068 Sequential Dynamics of Stearoyl-CoA Desaturase-1(SCD1)/Ligand Binding and Unbinding Mechanism: A Computational Study. 2021 Sep 30 4
21 31708235 Associations of maternal and fetal SCD-1 markers with infant anthropometry and maternal diet: Findings from the ROLO study. 2020 Jul 1
22 31936134 Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases. 2020 Jan 7 2
23 32097464 Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain. 2020 May 4 2
24 32122301 Fatty acid biosynthesis and transcriptional regulation of Stearoyl-CoA Desaturase 1 (SCD1) in buffalo milk. 2020 Mar 2 2
25 32133634 Inhibition of stearoyl-CoA desaturases suppresses follicular help T- and germinal center B- cell responses. 2020 Jul 1
26 32218693 ACSL1 affects Triglyceride Levels through the PPARγ Pathway. 2020 2
27 32315834 Structure-based virtual screening of natural products as potential stearoyl-coenzyme a desaturase 1 (SCD1) inhibitors. 2020 Jun 4
28 32452400 Region-specific changes in the mRNA and protein expression of LCPUFA biosynthesis enzymes and transporters in the placentae of women with preeclampsia. 2020 Jun 1
29 32464305 Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer. 2020 Aug 1
30 32726752 Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti-ferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer. 2020 Jul 29 2
31 32952654 Y-box binding protein 1 acts as a negative regulator of stearoyl CoA desaturase 1 in clear cell renal cell carcinoma. 2020 Nov 2
32 33041516 Reduction of stearoyl-CoA desaturase (SCD) contributes muscle atrophy through the excess endoplasmic reticulum stress in chronic kidney disease. 2020 Sep 1
33 33343508 ChREBP-Mediated Regulation of Lipid Metabolism: Involvement of the Gut Microbiota, Liver, and Adipose Tissue. 2020 1
34 33396940 Monounsaturated Fatty Acids in Obesity-Related Inflammation. 2020 Dec 30 1
35 30790642 Modulating Wnt signaling at the root: Porcupine and Wnt acylation. 2019 Jun 1
36 30871048 The Effect of an Infant Formula Supplemented with AA and DHA on Fatty Acid Levels of Infants with Different FADS Genotypes: The COGNIS Study. 2019 Mar 12 1
37 31019378 SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals. 2019 1
38 31199678 Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway. 2019 Sep 1
39 31284458 Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer. 2019 Jul 5 1
40 31481234 Clinical and biochemical relevance of monounsaturated fatty acid metabolism targeting strategy for cancer stem cell elimination in colon cancer. 2019 Oct 29 2
41 31678479 Fatty acid synthase and stearoyl-CoA desaturase-1 are conserved druggable cofactors of Old World Alphavirus genome replication. 2019 Dec 1
42 29530061 Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN. 2018 Mar 12 2
43 29869888 Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase. 2018 Jun 28 2
44 29955721 Iron, Oxidative Stress, and Δ9 Stearoyl-CoenzymeA Desaturase Index (C16:1/C16:0): An Analysis Applying the National Health and Nutrition Examination Survey 2003-04. 2018 Jan 2
45 30157936 FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression. 2018 Aug 29 1
46 30317781 [Research progress of stearoyl-CoA desaturase-1 on obesity and non-alcoholic fatty liver disease Abstract]. 2018 Jul 20 2
47 30453627 Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity. 2018 Nov 17 1
48 30475958 The association of fatty acid desaturase gene polymorphisms on long-chain polyunsaturated fatty acid composition in Indonesian infants. 2018 Nov 1 1
49 30656903 The role of stearoyl-CoA desaturase in the regulation of cardiac metabolism. 2018 Oct 25 2
50 27527582 The impact of fatty acid desaturase genotype on fatty acid status and cardiovascular health in adults. 2017 Feb 2