Title : Exosome-mediated delivery of SCD-1 siRNA promoted the death of anaplastic thyroid carcinoma cells via regulating ROS level.

Pub. Date : 2022 Feb

PMID : 34287816






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Stearoyl-CoA desaturase-1 (SCD-1) is one of major enzymes in the de novo synthesis of fatty acids and is related to cancer aggressiveness and poor patient prognosis. Fatty Acids stearoyl-CoA desaturase Homo sapiens
2 Stearoyl-CoA desaturase-1 (SCD-1) is one of major enzymes in the de novo synthesis of fatty acids and is related to cancer aggressiveness and poor patient prognosis. Fatty Acids stearoyl-CoA desaturase Homo sapiens
3 CONCLUSIONS: Exosomes loaded SCD-1 siRNA inhibited ATC cellular proliferation and promoted cellular apoptosis, and the mechanisms involved maybe the regulation of fatty acids metabolism and ROS level. Fatty Acids stearoyl-CoA desaturase Homo sapiens