coumarin

monoamine oxidase B ; Homo sapiens







23 Article(s)
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1 35168478 Structural exploration of selected C6 and C7-substituted coumarin isomers as selective MAO-B inhibitors. 2022 Feb 15 4
2 35195417 Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies. 2022 Mar 10 1
3 35300078 Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. 2022 Mar 10 2
4 33921982 Coumarin-Chalcone Hybrids as Inhibitors of MAO-B: Biological Activity and In Silico Studies. 2021 Apr 22 1
5 34879800 Multi-Target Directed Ligands (MTDLs): Promising Coumarin Hybrids for Alzheimer's Disease. 2021 1
6 32037726 Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents. 2020 Mar 18 1
7 31325784 Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease. 2019 Oct 15 2
8 29390885 Multi-targeted directed ligands for Alzheimer's disease: design of novel lead coumarin conjugates. 2018 Mar 2
9 29552556 Structure-Activity Relationship Analysis of 3-Phenylcoumarin-Based Monoamine Oxidase B Inhibitors. 2018 1
10 27744252 Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease. 2017 Jan 5 2
11 28291352 Understanding the Molecular Determinant of Reversible Human Monoamine Oxidase B Inhibitors Containing 2H-Chromen-2-One Core: Structure-Based and Ligand-Based Derived Three-Dimensional Quantitative Structure-Activity Relationships Predictive Models. 2017 Apr 24 1
12 28797881 Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors. 2017 Oct 20 2
13 26917219 Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer's disease. 2016 Apr 1 1
14 27347731 Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents. 2016 Jul 28 1
15 25812965 Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease. 2015 May 5 1
16 25857233 Inhibition effects of Vernonia cinerea active compounds against cytochrome P450 2A6 and human monoamine oxidases, possible targets for reduction of tobacco dependence. 2015 Apr 1
17 24934993 Coumarin hybrids as novel therapeutic agents. 2014 Aug 1 1
18 23589499 MAO inhibitory activity of 2-arylbenzofurans versus 3-arylcoumarins: synthesis, in vitro study, and docking calculations. 2013 Jun 1
19 24012182 Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. 2013 Oct 15 2
20 24231308 Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors. 2013 2
21 21684743 MAO inhibitory activity modulation: 3-Phenylcoumarins versus 3-benzoylcoumarins. 2011 Jul 15 1
22 17915852 Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs. 2007 Nov 15 3
23 17034132 Impact of species-dependent differences on screening, design, and development of MAO B inhibitors. 2006 Oct 19 1