Title : Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents.

Pub. Date : 2020 Mar 18

PMID : 32037726






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Half of the studied hybrids turned out to be selective monoamine oxidase B (hMAO-B) inhibitors in the low micro/nanomolar range, demonstrating that positions 3 (compounds 1-3) and 7 (compounds 8 and 10) of the coumarin scaffold are the most suitable for the incorporation of the alkynylamine chain. coumarin monoamine oxidase B Homo sapiens