Title : Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures.

Pub. Date : 2022 Mar 10

PMID : 35300078






2 Functional Relationships(s)
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1 Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. coumarin monoamine oxidase B Homo sapiens
2 Among previously reported micromolar or sub-micromolar coumarin-bearing dual inhibitors, compound 1 returned a tight-binding inhibition of MAO B (K i = 4.5 muM) and a +5.5 C increase in the enzyme T m value. coumarin monoamine oxidase B Homo sapiens