Title : MAO inhibitory activity of 2-arylbenzofurans versus 3-arylcoumarins: synthesis, in vitro study, and docking calculations.

Pub. Date : 2013 Jun

PMID : 23589499






1 Functional Relationships(s)
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1 3-(4"-Methoxyphenyl)-6-nitrocoumarin (15), with the same substitution pattern as that of compound 8, was found to be the most active MAO-B inhibitor of the coumarin series (IC50 =3 nM). coumarin monoamine oxidase B Homo sapiens