Dichloroacetic Acid

glutathione S-transferase zeta 1 ; Rattus norvegicus







12 Article(s)
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1 32873592 Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1. 2020 Nov 3
2 32873593 Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats. 2020 Nov 10
3 31524376 Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver. 2019 Oct 21 12
4 29626439 Regulation of dichloroacetate biotransformation in rat liver and extrahepatic tissues by GSTZ1 expression and chloride concentration. 2018 Jun 8
5 28163135 A Mechanism-Based Pharmacokinetic Enzyme Turnover Model for Dichloroacetic Acid Autoinhibition in Rats. 2017 May 4
6 20884751 Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1. 2011 Jan 9
7 16199472 Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal. 2006 Jan 3
8 15144222 Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: reaction of glyoxylate with amino acid nucleophiles. 2004 May 2
9 12730618 Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency. 2003 Jul 4
10 14599561 Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents. 2003 Nov 15 2
11 12019185 Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues. 2002 Jun 3
12 12441371 Nephrotoxicity of chlorofluoroacetic acid in rats. 2002 Dec 3