| 1 |
25744030 | Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells. | 2015 Apr 10 |
1 |
| 2 |
23340480 | Thrombopoietin modulates the proliferation, migration and cytokine profile of decidual cell subsets during early gestation. | 2013 Jun |
1 |
| 3 |
19857463 | Neuropilin-1 forms complexes with vascular endothelial growth factor receptor-2 during megakaryocytic differentiation of UT-7/TPO cells. | 2009 Dec 25 |
1 |
| 4 |
16150872 | Thrombopoietin stimulates migration and activates multiple signaling pathways in hepatoblastoma cells. | 2006 Jan |
1 |
| 5 |
15001470 | Induction of megakaryocytopoiesis and thrombocytopoiesis by JTZ-132, a novel small molecule with thrombopoietin mimetic activities. | 2004 Jul 1 |
2 |
| 6 |
11750880 | Thrombopoietin: a pan-hematopoietic cytokine. | 2002 Feb |
1 |
| 7 |
11874466 | Regulation of RAS in human platelets. Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation. | 2002 Mar |
1 |
| 8 |
11376875 | Role of phosphatidylinositol-3 kinase and its association with Gab1 in thrombopoietin-mediated up-regulation of platelet function. | 2001 May |
1 |
| 9 |
11402314 | Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo). | 2001 Apr 26 |
2 |
| 10 |
10651727 | Marked heterogeneity in protein levels and functional integrity of the thrombopoietin receptor c-mpl in polycythaemia vera. | 2000 Jan |
1 |
| 11 |
10720694 | Thrombopoietin induces the generation of distinct Stat1, Stat3, Stat5a and Stat5b homo- and heterodimeric complexes with different kinetics in human platelets. | 2000 Mar |
1 |
| 12 |
10918061 | A structure-function analysis of serine/threonine phosphorylation of the thrombopoietin receptor, c-Mpl. | 2000 Oct 13 |
1 |
| 13 |
10995006 | Expression of thrombopoietin receptor and its functional role in human B-precursor leukemia cells with 11q23 translocation or Philadelphia chromosome. | 2000 Sep |
1 |
| 14 |
11097834 | Thrombopoietin and interleukin-2 induce association of CRK with STAT5. | 2000 Nov 19 |
2 |
| 15 |
10194437 | Erythropoietin induces the tyrosine phosphorylation of GAB1 and its association with SHC, SHP2, SHIP, and phosphatidylinositol 3-kinase. | 1999 Apr 15 |
2 |
| 16 |
10224114 | Thrombopoietin signal transduction requires functional JAK2, not TYK2. | 1999 May 7 |
1 |
| 17 |
9459347 | Thrombopoietin activates human platelets and induces tyrosine phosphorylation of p80/85 cortactin. | 1998 Jan |
1 |
| 18 |
9475764 | Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera. | 1998 Feb 26 |
3 |
| 19 |
9623775 | Signal transduction by the peptide which mimics the activity of thrombopoietin. | 1998 May |
1 |
| 20 |
9663467 | Thrombopoietin supports in vitro erythroid differentiation via its specific receptor c-Mpl in a human leukemia cell line. | 1998 Jun |
2 |
| 21 |
9766506 | Effects of thrombopoietin, interleukin-3 and the kinase inhibitor K-252a on growth and polyploidization of the megakaryocytic cell line M-07e. | 1998 Oct |
2 |
| 22 |
9845531 | Thrombopoietin induces association of Crkl with STAT5 but not STAT3 in human platelets. | 1998 Dec 15 |
4 |
| 23 |
9885438 | Tyrosine phosphorylation of proteins in primary human myeloid leukemia cells stimulated by cytokines: analysis of the frequency of phosphorylation, and partial identification and semi-quantification of signaling molecules. | 1998 Dec |
1 |
| 24 |
11012189 | Defective c-Mpl signaling in the syndrome of thrombocytopenia with absent radii. | 1998 |
1 |
| 25 |
11012190 | A novel thrombopoietin signaling defect in polycythemia vera platelets. | 1998 |
3 |
| 26 |
9091296 | Tec protein-tyrosine kinase is involved in the thrombopoietin/c-Mpl signaling pathway. | 1997 Mar |
3 |
| 27 |
9096694 | Megakaryocyte growth and development factor (MGDF)-induced acute leukemia cell proliferation and clonal growth is associated with functional c-mpl. | 1997 Apr |
2 |
| 28 |
9108397 | Thrombopoietin and thrombin induce tyrosine phosphorylation of Vav in human blood platelets. | 1997 Apr 15 |
5 |
| 29 |
9120001 | Regulation of polymorphonuclear cell activation by thrombopoietin. | 1997 Apr 1 |
2 |
| 30 |
9226161 | Thrombopoietin in patients with congenital thrombocytopenia and absent radii: elevated serum levels, normal receptor expression, but defective reactivity to thrombopoietin. | 1997 Jul 15 |
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| 31 |
8555464 | Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets. | 1996 Jan 15 |
4 |
| 32 |
8639823 | Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO. | 1996 Jun 1 |
1 |
| 33 |
8645238 | Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation. | 1996 May 15 |
3 |
| 34 |
8695851 | p120c-cbl is present in human blood platelets and is differentially involved in signaling by thrombopoietin and thrombin. | 1996 Aug 15 |
7 |
| 35 |
8843545 | Thrombopoietin modulates platelet activation in vitro through protein-tyrosine phosphorylation. | 1996 Jul |
12 |
| 36 |
8874206 | The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells. | 1996 Oct 15 |
1 |
| 37 |
8877093 | Differentiation induced by the c-Mpl cytokine receptor is blocked by mutant Shc adaptor protein. | 1996 Sep |
2 |
| 38 |
8898102 | Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation. | 1996 Oct 21 |
1 |
| 39 |
8943867 | Crkl is constitutively tyrosine phosphorylated in platelets from chronic myelogenous leukemia patients and inducibly phosphorylated in normal platelets stimulated by thrombopoietin. | 1996 Dec 1 |
1 |
| 40 |
7488109 | TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules. | 1995 Nov 2 |
4 |
| 41 |
7492761 | Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. | 1995 Dec 1 |
3 |
| 42 |
7543416 | The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases. | 1995 Aug |
2 |
| 43 |
7544303 | Thrombopoietin (TPO) induces tyrosine phosphorylation and activation of STAT5 and STAT3. | 1995 Aug 14 |
4 |
| 44 |
7589510 | Thrombopoietin, c-Mpl ligand, induces tyrosine phosphorylation of Tyk2, JAK2, and STAT3, and enhances agonists-induced aggregation in platelets in vitro. | 1995 Oct 23 |
4 |
| 45 |
7780132 | Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2. | 1995 Jun 15 |
2 |
| 46 |
7795229 | Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets. | 1995 Jul 1 |
3 |
| 47 |
8526916 | Thrombopoietin induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in a human thrombopoietin-dependent cell line. | 1995 Dec 5 |
3 |
| 48 |
8578535 | Megakaryocyte growth and development factor (MGDF) moderately enhances in-vitro platelet aggregation. | 1995 Oct 1 |
2 |
| 49 |
8772234 | Modulation of platelet activation in vitro by thrombopoietin. | 1995 Dec |
2 |