Title : Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo).

Pub. Date : 2001 Apr 26

PMID : 11402314






2 Functional Relationships(s)
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1 In this study, we show that upon thrombopoietin (Tpo) stimulation the two adapter proteins Gab1 and Gab2 are strongly tyrosine phosphorylated and associated with Shc, SHP2, PI 3-kinase and Grb2 in mpl-expressing UT7 cells. Tyrosine thrombopoietin Homo sapiens
2 In this study, we show that upon thrombopoietin (Tpo) stimulation the two adapter proteins Gab1 and Gab2 are strongly tyrosine phosphorylated and associated with Shc, SHP2, PI 3-kinase and Grb2 in mpl-expressing UT7 cells. Tyrosine thrombopoietin Homo sapiens