Pub. Date : 1995 Dec 1
PMID : 7492761
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have observed that TPO treatment of human platelets resulted in tyrosine phosphorylation of several cellular proteins, including the c-Mpl receptor and the 85-kD subunit of phosphatidylinositol 3-kinase (PI3-K). | Tyrosine | thrombopoietin | Homo sapiens |
| 2 | TPO stimulated this tyrosine phosphorylation in a time-dependent manner, reaching a maximum in 5 minutes. | Tyrosine | thrombopoietin | Homo sapiens |
| 3 | The tyrosine phosphorylation of PI 3-K was dependent on the concentration of TPO and reached a maximum at concentrations between 50 and 100 ng/mL. | Tyrosine | thrombopoietin | Homo sapiens |