Bupropion

cytochrome P450 family 2 subfamily D member 6 ; Homo sapiens







28 Article(s)
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1 35512805 Stereoselective metabolism of bupropion to active metabolites in cellular fractions of human liver and intestine. 2022 May 5 1
2 33161206 Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96]. 2021 Jan 2
3 33905640 Dose-Dependent Inhibition of CYP2D6 by Bupropion in Patients With Depression. 2021 May-Jun 01 5
4 34015277 The Pharmacokinetics of Gefitinib in a Chinese Cancer Population Group: A Virtual Clinical Trials Population Study. 2021 Oct 1
5 30842914 Evaluation of dextromethorphan with select antidepressant therapy for the treatment of depression in the acute care psychiatric setting. 2019 Mar 1
6 28876959 Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion. 2018 Sep 3
7 27836670 In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation. 2017 Jan 1 9
8 29054049 Individual variability in clinical effect and tolerability of opioid analgesics - Importance of drug interactions and pharmacogenetics. 2017 Oct 1
9 29267251 Prediction of Drug-Drug Interactions with Bupropion and Its Metabolites as CYP2D6 Inhibitors Using a Physiologically-Based Pharmacokinetic Model. 2017 Dec 21 2
10 26967321 Impact of Cytochrome P450 2D6 Function on the Chiral Blood Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine (MDMA) and Its Phase I and II Metabolites in Humans. 2016 1
11 27255113 Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers. 2016 Aug 3
12 27300331 Assessment of a Potential Pharmacokinetic Interaction between Nebivolol and Bupropion in Healthy Volunteers. 2016 1
13 27518170 Evaluation of a Potential Metabolism-Mediated Drug-Drug Interaction Between Atomoxetine and Bupropion in Healthy Volunteers. 2016 Apr-Jun 1
14 25565674 Effect of CYP2B6*6 on Steady-State Serum Concentrations of Bupropion and Hydroxybupropion in Psychiatric Patients: A Study Based on Therapeutic Drug Monitoring Data. 2015 Oct 1
15 24396053 Observations on the urine metabolic profile of codeine in pain patients. 2014 Mar 1
16 24237812 Lack of impairment due to confirmed codeine use prior to a motor vehicle accident: role of pharmacogenomics. 2013 Nov 1
17 22171584 Clinically significant drug interactions with newer antidepressants. 2012 Jan 1 1
18 21946596 [Interactions between metoprolol and antidepressants]. 2011 Sep 20 1
19 20208386 System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: human hepatocytes versus liver microsomes versus recombinant enzymes. 2010 2
20 20880642 Managing menopausal symptoms and depression in tamoxifen users: implications of drug and medicinal interactions. 2010 Dec 1
21 18420781 An in vitro mechanistic study to elucidate the desipramine/bupropion clinical drug-drug interaction. 2008 Jul 5
22 18691982 Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: an update. 2008 Jul 1
23 17009913 Bupropion: pharmacology and therapeutic applications. 2006 Sep 2
24 15876900 Inhibition of CYP2D6 activity by bupropion. 2005 Jun 7
25 16368442 Bupropion for major depressive disorder: Pharmacokinetic and formulation considerations. 2005 Nov 1
26 12021638 Change from the CYP2D6 extensive metabolizer to the poor metabolizer phenotype during treatment With bupropion. 2002 Jun 5
27 10997936 CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants. 2000 Oct 1
28 8885123 Bupropion plasma levels and CYP2D6 phenotype. 1996 Oct 1