Title : The Pharmacokinetics of Gefitinib in a Chinese Cancer Population Group: A Virtual Clinical Trials Population Study.

Pub. Date : 2021 Oct

PMID : 34015277






1 Functional Relationships(s)
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1 When assessing the impact of 2D6 phenotypes on bupropion mediated CYP 2D6 DDI in Chinese cancer population, we found that AUC increased by at least 60% in extensive metabolizers (EM) and 30% in IM. Bupropion cytochrome P450 family 2 subfamily D member 6 Homo sapiens