Title : Individual variability in clinical effect and tolerability of opioid analgesics - Importance of drug interactions and pharmacogenetics.

Pub. Date : 2017 Oct

PMID : 29054049






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Concomitant use of CYP inhibitors (e.g. paroxetine, fluoxetine and bupropion) or inducers (e.g. carbamazepine, phenobarbital and phenytoin) could counteract the clinical effect or trigger side effects of analgesics in the same manner as genetically determined differences in CYP2D6-mediated metabolism of many opioids. Bupropion cytochrome P450 family 2 subfamily D member 6 Homo sapiens