Title : Evaluation of a Potential Metabolism-Mediated Drug-Drug Interaction Between Atomoxetine and Bupropion in Healthy Volunteers.

Pub. Date : 2016 Apr-Jun

PMID : 27518170






1 Functional Relationships(s)
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1 CONCLUSIONS: These results demonstrated that the effect of bupropion on CYP2D6 activity was responsible for an increased systemic exposure to atomoxetine (5.1-fold) and also for a decreased exposure to its main metabolite (1.5-fold). Bupropion cytochrome P450 family 2 subfamily D member 6 Homo sapiens