290 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
251 | 8615170 | Effects of catechol-O-methyltransferase (COMT) inhibition on the pharmacokinetics of L-DOPA. | 1996 | 2 |
252 | 8726541 | Effect of one month's treatment with peripherally acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients. | 1996 Jun | 2 |
253 | 8807664 | Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. | 1996 Jun | 2 |
254 | 8836986 | The metabolism of L-DOPA and L-threo-3,4-dihydroxyphenylserine and their effects on monoamines in the human brain: analysis of the intraventricular fluid from parkinsonian patients. | 1996 Jul | 2 |
255 | 8941353 | No association between Parkinson's disease and low-activity alleles of catechol O-methyltransferase. | 1996 Nov 21 | 1 |
256 | 7651456 | Effects of tolcapone in Parkinson's patients taking L-dihydroxyphenylalanine/carbidopa and selegiline. | 1995 May | 1 |
257 | 8527287 | Pharmacokinetic-pharmacodynamic interaction between the COMT inhibitor tolcapone and single-dose levodopa. | 1995 Sep | 1 |
258 | 8635184 | Acute administration of levodopa-benserazide and tolcapone, a COMT inhibitor, Parkinson's disease. | 1995 Jun | 2 |
259 | 8665534 | Effect of entacapone, a COMT inhibitor, on the pharmacokinetics and metabolism of levodopa after administration of controlled-release levodopa-carbidopa in volunteers. | 1995 Feb | 1 |
260 | 8665546 | Acute effects of COMT inhibition on L-DOPA pharmacokinetics in patients treated with carbidopa and selegiline. | 1995 Aug | 2 |
261 | 8787797 | Pharmacokinetic model of oral levodopa and role of carbidopa in parkinsonian patients. | 1995 Dec | 1 |
262 | 7834959 | [The effect of droxidopa on the monoamine metabolsim in the human brain]. | 1994 Oct | 2 |
263 | 7952244 | New medical and surgical treatments for Parkinson's disease. | 1994 Aug | 2 |
264 | 8035323 | Ethnic differences in erythrocyte catechol-O-methyltransferase activity in black and white Americans. | 1994 Jul | 2 |
265 | 8070503 | Low catechol-O-methyltransferase activity in a Saami population. | 1994 | 1 |
266 | 8126502 | Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease. | 1994 Feb | 4 |
267 | 8127373 | Crystal structure of catechol O-methyltransferase. | 1994 Mar 24 | 1 |
268 | 8190296 | Effect of peripheral catechol-O-methyltransferase inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients. | 1994 May | 5 |
269 | 27520516 | Clinical Potential of Catechol-OMethyltransferase (COMT) Inhibitors as Adjuvants in Parkinson's Disease. | 1994 Mar | 2 |
270 | 8112370 | Effect of entacapone, a COMT inhibitor, on the pharmacokinetics of levodopa and on cardiovascular responses in patients with Parkinson's disease. | 1993 | 1 |
271 | 8255478 | Catechol-O-methyltransferase inhibitor tolcapone prolongs levodopa/carbidopa action in parkinsonian patients. | 1993 Dec | 1 |
272 | 8341294 | Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa. | 1993 Jul | 2 |
273 | 8477410 | The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers. | 1993 Apr | 3 |
274 | 1584187 | Treatment strategies for extension of levodopa effect. | 1992 May | 1 |
275 | 1734304 | [18F]-6-fluorodopa PET scanning in Parkinson's disease after selective COMT inhibition with nitecapone (OR-462). | 1992 Jan | 1 |
276 | 1875781 | Catechol-O-methyltransferase and aromatic L-amino acid decarboxylase activities in human gastrointestinal tissues. | 1991 | 3 |
277 | 1884738 | Inhibition of human erythrocyte and gastroduodenal catechol-O-methyltransferase activity by nitecapone. | 1991 | 1 |
278 | 1958292 | (-)-Deprenyl treatment of patients with Parkinson's disease does not affect erythrocyte catechol-O-methyl transferase activity. | 1991 | 3 |
279 | 2272023 | Effect of a novel catechol-O-methyltransferase inhibitor, nitecapone, on the metabolism of L-dopa in healthy volunteers. | 1990 Oct | 2 |
280 | 2289048 | L-dopa as substrate for human duodenal catechol-O-methyltransferase and aromatic L-amino acid decarboxylase. | 1990 Nov | 1 |
281 | 6437857 | The pharmacology of Parkinson's disease: basic aspects and recent advances. | 1984 Nov 15 | 1 |
282 | 6714437 | Human pharmacogenetics of methyl conjugation. | 1984 May 15 | 1 |
283 | 6734032 | Difference in erythrocyte catechol-O-methyltransferase activity between Orientals and Caucasians: difference in levodopa tolerance. | 1984 Jun | 2 |
284 | 7121609 | Catechol-O-methyltransferase inhibition by U-0521 increases striatal utilization of levodopa. | 1982 Jul | 1 |
285 | 7137962 | 3-O-methyldopa blocks dopa metabolism in rat corpus striatum. | 1982 Sep | 1 |
286 | 7296879 | Determination of free and conjugated catecholamines and L-3,4-dihydroxyphenylalanine in plasma and urine: evidence for a catechol-O-methyltransferase inhibitor in uraemia. | 1981 Sep | 1 |
287 | 7398195 | Catechol-O-methyltransferase activity: a determinant of levodopa response. | 1980 Aug | 5 |
288 | 847319 | [Abnormal movements of patients with Parkinsonism treated with L-dopa and anomalies of dopamine metabolism]. | 1977 Jan | 1 |
289 | 5016575 | Metabolism of L-dopa after inhibition of catechol-O-methyl transferase. | 1972 Jan | 1 |
290 | 5112212 | Potentiation of the L-Dopa effect in man by the use of catechol-O-methyltransferase inhibitors. | 1971 Oct | 1 |