Title : Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.

Pub. Date : 1998 Mar 15

PMID : 9494076






2 Functional Relationships(s)
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1 In contrast, the distal three tyrosines in CD28 are required for optimal IL2 production as well as for optimal activation of the LCK and EMT/ITK tyrosine kinases. Tyrosine interleukin 2 Homo sapiens
2 Taken together the data indicate that the distal three tyrosines in CD28 are integral to the activation of LCK and EMT/ITK and for subsequent IL2 production. Tyrosine interleukin 2 Homo sapiens