Heparin

serpin family D member 1 ; Homo sapiens







74 Article(s)
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1 27301751 Blocking inhibition of prothrombinase by tissue factor pathway inhibitor alpha: a procoagulant property of heparins. 2016 Oct 2
2 25130770 Heparin co-factor II enhances cell motility and promotes metastasis in non-small cell lung cancer. 2015 Jan 2
3 22206940 Fluorescent reporters of thrombin, heparin cofactor II, and heparin binding in a ternary complex. 2012 Feb 15 2
4 21805439 Heparin cofactor II: discovery, properties, and role in controlling vascular homeostasis. 2011 Jun 1
5 20053992 Sucrose octasulfate selectively accelerates thrombin inactivation by heparin cofactor II. 2010 Mar 12 1
6 20670608 Glycosaminoglycan-binding properties and kinetic characterization of human heparin cofactor II expressed in Escherichia coli. 2010 Nov 15 1
7 15869786 Investigating serpin-enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II. 2006 3
8 15078125 Structural and conformational aspects of the anticoagulant and anti-thrombotic activity of heparin and dermatan sulfate. 2004 6
9 15247982 Studies on the effect of calcium in interactions between heparin and heparin cofactor II using surface plasmon resonance. 2004 Jul 6
10 15371417 The heparin binding properties of heparin cofactor II suggest an antithrombin-like activation mechanism. 2004 Nov 26 6
11 11856753 Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote intramolecular interactions during glycosaminoglycan binding and thrombin inhibition. 2002 May 31 3
12 12095635 Contribution of basic residues of the A helix of heparin cofactor II to heparin- or dermatan sulfate-mediated thrombin inhibition. 2002 Jul 3 2
13 12413592 Inhibition of a thrombin anion-binding exosite-2 mutant by the glycosaminoglycan-dependent serpins protein C inhibitor and heparin cofactor II. 2002 Jul 15 3
14 11583326 Selective and sustained inhibition of surface-bound thrombin activity by intimatan/heparin cofactor II and its relevance to assessing systemic anticoagulation in vivo, ex vivo and in vitro. 2001 Sep 2
15 10753952 Activation of heparin cofactor II by calcium spirulan. 2000 Apr 14 2
16 10209287 Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions. 1999 Apr 12 3
17 10349131 [Heparin cofactor II, a thrombin inhibitor with a still not clarified physiologic role]. 1999 1
18 10488098 Comparison of heparin- and dermatan sulfate-mediated catalysis of thrombin inactivation by heparin cofactor II. 1999 Sep 24 5
19 10494755 Hereditary homozygous heparin cofactor II deficiency and the risk of developing venous thrombosis. 1999 Sep 2
20 10574918 Enhancement of heparin cofactor II anticoagulant activity. 1999 Dec 3 2
21 9485475 Ligand binding to thrombin exosite II induces dissociation of the thrombin-heparin cofactor II(L444R) complex. 1998 Mar 3 11
22 9641623 Anticoagulant activity of dextran derivatives. 1998 Jul 1
23 9813026 Role of thrombin anion-binding exosite-I in the formation of thrombin-serpin complexes. 1998 Nov 20 1
24 9843172 Isolation of frog and chicken cDNAs encoding heparin cofactor II. 1998 Nov 2
25 8995378 Heparin promotes proteolytic inactivation by thrombin of a reactive site mutant (L444R) of recombinant heparin cofactor II. 1997 Jan 10 1
26 9031720 Mechanism of thrombin inhibition by antithrombin and heparin cofactor II in the presence of heparin. 1997 Feb 1
27 9079643 Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II. 1997 Mar 28 1
28 9306616 Interaction of fucoidan with proteases and inhibitors of coagulation and fibrinolysis. 1997 Sep 1 1
29 9353333 Inhibition of meizothrombin and meizothrombin(desF1) by heparin cofactor II. 1997 Nov 7 1
30 8562924 Molecular and cellular basis for type I heparin cofactor II deficiency (heparin cofactor II Awaji). 1996 Feb 1 2
31 8792767 Arterial smooth muscle cell heparan sulfate proteoglycans accelerate thrombin inhibition by heparin cofactor II. 1996 Sep 2
32 8902986 A heparin cofactor II mutation (HCII Rimini) combined with factor V Leiden or type I protein C deficiency in two unrelated thrombophilic subjects. 1996 Oct 1
33 9112638 Prevalence of heparin cofactor II deficiency in patients with a history of venous thrombosis. 1996 Jan-Feb 2
34 7588997 Effect of sulfated xylans during the interaction of [125I]-thrombin with antithrombin III or heparin cofactor II of human plasma. 1995 Jan-Mar 1
35 7908224 Murine heparin cofactor II: purification, cDNA sequence, expression, and gene structure. 1994 Mar 29 2
36 8017769 The interaction of glycosaminoglycans with heparin cofactor II. 1994 Apr 18 3
37 8259546 The additive effect of low molecular weight heparins on thrombin inhibition by dermatan sulfate. 1993 Sep 1 1
38 8335699 Affinity chromatography of sulphated polysaccharides separately fractionated on antithrombin III and heparin cofactor II immobilized on concanavalin A--sepharose. 1993 Jun 2 2
39 8362268 Antithrombin III- and heparin cofactor II-mediated anticoagulant and antiprotease actions of heparin and its synthetic analogues. 1993 1
40 8429040 Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity. 1993 Feb 15 1
41 1381850 Modulation of heparin cofactor II activity by glycosaminoglycans and adhesive glycoproteins. 1992 Jun 1 4
42 1442260 The interaction of glycosaminoglycans with heparin cofactor II: structure and activity of a high-affinity dermatan sulfate hexasaccharide. 1992 3
43 1521342 An enzyme-linked immunosorbent assay for heparin cofactor II (HCII). Application to the measurement of HCII in clinical materials. 1992 Jan 31 2
44 1671335 Complete nucleotide sequence of the gene for human heparin cofactor II and mapping to chromosomal band 22q11. 1991 Feb 5 2
45 1718466 Heparin cofactor II: an acute phase reactant in patients with deep vein thrombosis. 1991 Jun 1
46 2045458 Purification of heparin cofactor II from human plasma. 1991 Feb 22 2
47 1962908 Effect of low molecular weight heparin preparations on the inhibition of thrombin by heparin cofactor II. 1990 Oct 4
48 1962909 Comparative studies of heparin cofactor activity toward antithrombin III and heparin cofactor II, and antithrombin III affinity between low molecular weight heparin and unfractionated heparin. 1990 Oct 2
49 2096488 Increased heparin cofactor II levels in women taking oral contraceptives. 1990 Nov 30 2
50 2196322 Characteristics of the chemotactic activity of heparin cofactor II proteolysis products. 1990 Aug 1