Title : Heparin co-factor II enhances cell motility and promotes metastasis in non-small cell lung cancer.

Pub. Date : 2015 Jan

PMID : 25130770






2 Functional Relationships(s)
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1 We further showed that HCII could up-regulate cancer cell migration through the activation of PI3K, which acts upstream of Rac1 and Cdc42, and this effect could be blocked by heparin. Heparin serpin family D member 1 Homo sapiens
2 We suggest that HCII is a novel metastasis enhancer and may be used as a prognostic predictor for heparin treatment in NSCLC. Heparin serpin family D member 1 Homo sapiens