Title : Fluorescent reporters of thrombin, heparin cofactor II, and heparin binding in a ternary complex.

Pub. Date : 2012 Feb 15

PMID : 22206940






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Thrombin inactivation by heparin cofactor II (HCII) is accelerated by ternary complex formation with heparin. Heparin serpin family D member 1 Homo sapiens
2 These studies demonstrate that binding of HCII to the thrombin heparin complex is dramatically enhanced compared with heparin binding alone and that exosite I is still available for ligand or HCII binding when both heparin binding sites on thrombin are saturated. Heparin serpin family D member 1 Homo sapiens