Cysteine

glyceraldehyde-3-phosphate dehydrogenase ; Homo sapiens







77 Article(s)
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1 33850276 Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase. 2022 Feb 2
2 35562998 Mechanism of GAPDH Redox Signaling by H2O2 Activation of a Two-Cysteine Switch. 2022 Apr 21 1
3 33601275 Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation. 2021 May 3
4 34827652 Modification of Glyceraldehyde-3-Phosphate Dehydrogenase with Nitric Oxide: Role in Signal Transduction and Development of Apoptosis. 2021 Nov 8 2
5 29848267 Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate Dehydrogenase. 2020 2
6 32536603 Ionizing Radiation-induced Proteomic Oxidation in Escherichia coli. 2020 Aug 1
7 32802964 Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid. 2020 1
8 32898762 Covalent inhibitors of GAPDH: From unspecific warheads to selective compounds. 2020 Dec 1 2
9 33170008 Monohaloacetic Acids and Monohaloacetamides Attack Distinct Cellular Proteome Thiols. 2020 Dec 1 1
10 30654934 Glutathione and cysteines suppress cytotoxicity of gas phase of cigarette smoke by direct reacting with unsaturated carbonyl compounds in the gas phase. 2019 Feb 19 2
11 29298351 Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase. 2018 4
12 29408361 Binding of alpha-synuclein to partially oxidized glyceraldehyde-3-phosphate dehydrogenase induces subsequent inactivation of the enzyme. 2018 Mar 15 1
13 30254002 Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation. 2018 Dec 2
14 30395437 Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3-Bromopyruvate Targets beyond Glycolysis. 2018 Nov 16 2
15 30504682 2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) Disrupts Carbohydrate Metabolism of HeLa Cells by Adduct Formation with Intracellular Free Sulfhydryl-Groups, and Induces ATP Depletion and Necrosis. 2018 1
16 28079302 Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule. 2017 Aug 1
17 28167533 Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death. 2017 Mar 17 8
18 28404743 Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death. 2017 Jul 2
19 28450161 A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells. 2017 Aug 1 1
20 26725192 Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death. 2016 Feb 29 4
21 27405778 Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. 2016 Sep 22 1
22 25196942 Thiol-based regulation of glyceraldehyde-3-phosphate dehydrogenase in blood bank-stored red blood cells: a strategy to counteract oxidative stress. 2015 Mar 2
23 25391652 Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade. 2015 Jan 2 2
24 25416785 Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues. 2015 Jan 16 1
25 26453916 Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is inactivated by S-sulfuration in vitro. 2015 Dec 7
26 26555470 Low Concentrations of Hydrogen Peroxide Activate the Antioxidant Defense System in Human Sperm Cells. 2015 Sep 1
27 24059224 Effect of resveratrol and tiron on the inactivation of glyceraldehyde-3- phosphate dehydrogenase induced by superoxide anion radical. 2014 1
28 24662796 [The biological significance of oxidative modifications of cysteine residues in proteins illustrated with the example of glyceraldehyde-3-phosphate dehydrogenase]. 2014 Mar 12 6
29 24769698 Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa. 2014 Jul 2
30 22457359 Thioredoxin-1 regulates cellular heme insertion by controlling S-nitrosation of glyceraldehyde-3-phosphate dehydrogenase. 2012 May 11 1
31 22534308 Glyceraldehyde-3-phosphate, a glycolytic intermediate, prevents cells from apoptosis by lowering S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase. 2012 Apr 2
32 22771119 Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation. 2012 Aug 24 1
33 23009681 Myeloperoxidase catalyzes the conjugation of serotonin to thiols via free radicals and tryptamine-4,5-dione. 2012 Nov 19 2
34 21148632 Novel oxidative modifications in redox-active cysteine residues. 2011 Mar 2
35 20946853 Two-component signaling to the stress MAP kinase cascade in fission yeast. 2010 1
36 20972425 GAPDH mediates nitrosylation of nuclear proteins. 2010 Nov 2
37 19837666 Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death. 2009 Dec 4 2
38 18163542 Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produce DNA-protein cross-links but not mutations. 2008 Feb 2
39 18183946 Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase. 2008 Feb 1
40 18298375 Investigation of glyceraldehyde-3-phosphate dehydrogenase from human sperms. 2008 Feb 1
41 18771724 Covalent modification of proteins by green tea polyphenol (-)-epigallocatechin-3-gallate through autoxidation. 2008 Nov 15 1
42 18776186 Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1. 2008 Nov 7 1
43 18809573 Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability. 2008 Dec 1
44 17559999 Antioxidant and prooxidant effects of quercetin on glyceraldehyde-3-phosphate dehydrogenase. 2007 Oct 1
45 17613523 The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death. 2007 Sep 7 6
46 16682416 Reversible post-translational modification of proteins by nitrated fatty acids in vivo. 2006 Jul 21 5
47 15677321 Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH. 2005 Feb 1 1
48 16128592 Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance. 2005 Sep 6 1
49 12882642 Acceleration of glycolysis in the presence of the non-phosphorylating and the oxidized phosphorylating glyceraldehyde-3-phosphate dehydrogenases. 2003 May 1
50 12914777 Ascorbate-induced oxidation of glyceraldehyde-3-phosphate dehydrogenase. 2003 Aug 29 1