Pub. Date : 2020 Dec 1
PMID : 32898762
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Covalent modification on different amino acids of GAPDH, in particular on cysteine residues, can lead to a modulation of the enzyme activity. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 2 | In this work we report an extensive overview of the latest advances on the numerous compounds able to inhibit GAPDH through the covalent binding to cysteine residues, ranging from endogenous metabolites and xenobiotics, which may serve as pharmacological tools to actual drug-like compounds with promising therapeutic perspectives. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |