Title : Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3-Bromopyruvate Targets beyond Glycolysis.

Pub. Date : 2018 Nov 16

PMID : 30395437






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We previously identified four cysteine residues in GAPDH that are alkylated by 3BP, resulting in its inactivation. Cysteine glyceraldehyde-3-phosphate dehydrogenase Homo sapiens
2 This result indicates that GAPDH may not be the only relevant target and is consistent with the chemical reactivity of 3BP that should result in the modification of cysteine residues in many different proteins. Cysteine glyceraldehyde-3-phosphate dehydrogenase Homo sapiens