Pub. Date : 2015 Dec
PMID : 26453916
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One of the first proteins shown to be modified by H2S was glyceraldehyde 3-phosphate dehydrogenase (GAPDH) [1] where the S-sulfuration of the active site cysteine (Cys 152) resulted in ~7-fold increase in the activity of the enzyme. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 2 | One of the first proteins shown to be modified by H2S was glyceraldehyde 3-phosphate dehydrogenase (GAPDH) [1] where the S-sulfuration of the active site cysteine (Cys 152) resulted in ~7-fold increase in the activity of the enzyme. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 3 | One of the first proteins shown to be modified by H2S was glyceraldehyde 3-phosphate dehydrogenase (GAPDH) [1] where the S-sulfuration of the active site cysteine (Cys 152) resulted in ~7-fold increase in the activity of the enzyme. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 4 | One of the first proteins shown to be modified by H2S was glyceraldehyde 3-phosphate dehydrogenase (GAPDH) [1] where the S-sulfuration of the active site cysteine (Cys 152) resulted in ~7-fold increase in the activity of the enzyme. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 5 | S-sulfuration of GAPDH occurred at Cys 247 after sulfide treatment, Cys 156 and Cys 247 after polysulfide treatment. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 6 | Treatment of glutathione disulfide oxidized GAPDH with polysulfide also produced S-sulfuration of Cys 156. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 7 | Treatment of a C156S mutant of GAPDH with sulfide and polysulfide resulted in S-sulfuration of Cys 152, which also caused a decrease and not an increase in enzymatic activity. | Cysteine | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |