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34278499 | [Corrigendum] Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells. | 2021 Sep |
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27324990 | Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas. | 2016 Oct |
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25289695 | Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor. | 2014 |
1 |
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22471932 | Ginsenoside-Rp1 inhibits platelet activation and thrombus formation via impaired glycoprotein VI signalling pathway, tyrosine phosphorylation and MAPK activation. | 2012 Sep |
1 |
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21894146 | Spleen tyrosine kinase promotes acute neutrophil-mediated glomerular injury via activation of JNK and p38 MAPK in rat nephrotoxic serum nephritis. | 2011 Dec |
1 |
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20554527 | Tyrosines in the carboxyl terminus regulate Syk kinase activity and function. | 2010 Aug 20 |
16 |
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20828828 | Syk and Lyn mediate distinct Syk phosphorylation events in FcɛRI-signal transduction: implications for regulation of IgE-mediated degranulation. | 2010 Nov-Dec |
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20091279 | Distinct effects on M2-type pyruvate kinase are involved in the dimethylsulfoxide-induced modulation of cellular proliferation and degranulation of mast cells. | 2009 Nov |
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17977829 | TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells. | 2007 Dec 28 |
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16002993 | Selective inhibition of Fcepsilon RI-mediated mast cell activation by a truncated variant of Cbl-b related to the rat model of type 1 diabetes mellitus. | 2005 Jun |
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15162432 | Involvement of filamentous actin in setting the threshold for degranulation in mast cells. | 2004 Jun |
1 |
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15339843 | Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation. | 2004 Dec 15 |
1 |
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15489638 | Alpha-melanocyte stimulating hormone protects against H2O2-induced inhibition of wound restitution in IEC-6 cells via a Syk kinase- and NF-kappabeta-dependent mechanism. | 2004 Nov |
1 |
| 14 |
11809740 | A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor. | 2002 Feb |
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12145291 | Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells. | 2002 Oct 4 |
2 |
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12217386 | Modeling the early signaling events mediated by FcepsilonRI. | 2002 Sep |
1 |
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12225366 | krox-20/egr-2 is up-regulated following non-specific and homophilic adhesion in rat macrophages. | 2002 Sep |
1 |
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11137136 | Tyrosine phosphorylation of the linker for activator of T cells in mast cells by stimulation with the high affinity IgE receptor. | 2001 Jan 1 |
1 |
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11165236 | Syk protein-tyrosine kinase is involved in neuron-like differentiation of embryonal carcinoma P19 cells. | 2001 Feb 2 |
1 |
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11465115 | The protein tyrosine kinase syk activity is reduced by clustering the mast cell function-associated antigen. | 2001 May |
3 |
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10605028 | Point mutation of a tyrosine in the linker region of Syk results in a gain of function. | 2000 Jan 1 |
5 |
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10640770 | Positive regulation of c-Jun N-terminal kinase and TNF-alpha production but not histamine release by SHP-1 in RBL-2H3 mast cells. | 2000 Feb 1 |
1 |
| 23 |
10731700 | Purification of a 72-kDa protein-tyrosine kinase from rat liver and its identification as Syk: involvement of Syk in signaling events of hepatocytes. | 2000 Feb |
2 |
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9886384 | Lyn dissociation from phosphorylated Fc epsilon RI subunits: a new regulatory step in the Fc epsilon RI signaling cascade revealed by studies of Fc epsilon RI dimer signaling activity. | 1999 Jan 1 |
2 |
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10447762 | Syk and paxillin are differentially phosphorylated following adhesion to the plastic substrate in rat alveolar macrophages. | 1999 Jul |
5 |
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9604011 | Evidence for involvement of two isoforms of Syk protein-tyrosine kinase in signal transduction through the high affinity IgE receptor on rat basophilic leukemia cells. | 1998 Jun |
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9780214 | Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity. | 1998 Oct 15 |
6 |
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9022035 | Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fc epsilon receptors. | 1997 Jan |
2 |
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9032405 | Large scale isolation of intact rat basophilic leukemia (RBL-2H3) cells. | 1997 Feb 14 |
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9153264 | The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor. | 1997 May 23 |
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9356485 | ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of fcepsilon receptor I-mediated activation of Syk. | 1997 Nov 11 |
2 |
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9367826 | Fc epsilon RI aggregation induces tyrosine phosphorylation of a novel 72 kDa protein downstream of Syk. | 1997 Oct 29 |
4 |
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9369226 | Insulin dependent tyrosine phosphorylation of the tyrosine internalisation motif of TGN38 creates a specific SH2 domain binding site. | 1997 Oct 13 |
1 |
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9379041 | Syk-independent tyrosine phosphorylation and association of the protein tyrosine phosphatases SHP-1 and SHP-2 with the high affinity IgE receptor. | 1997 Nov 1 |
1 |
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9405454 | Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling. | 1997 Dec 19 |
2 |
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9464827 | Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells. | 1997 Dec |
2 |
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8663278 | Syk-dependent phosphorylation of Shc. A potential link between FcepsilonRI and the Ras/mitogen-activated protein kinase signaling pathway through SOS and Grb2. | 1996 Jul 5 |
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8691151 | Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells. | 1996 Jul 1 |
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8805635 | Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells. | 1996 Sep 15 |
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| 40 |
8910399 | Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor. | 1996 Nov 1 |
4 |
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8920860 | Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells. | 1996 Nov 1 |
5 |
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7528327 | Interaction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RI. | 1995 Jan |
15 |
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7532280 | Clustering of Syk is sufficient to induce tyrosine phosphorylation and release of allergic mediators from rat basophilic leukemia cells. | 1995 Mar |
4 |
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7537732 | Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. | 1995 May 5 |
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7594547 | Protein tyrosine phosphatase activity associates with the high affinity IgE receptor and dephosphorylates the receptor subunits, but not Lyn or Syk. | 1995 Dec 1 |
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7623809 | Activation of the high-affinity immunoglobulin E receptor Fc epsilon RI in RBL-2H3 cells is inhibited by Syk SH2 domains. | 1995 Aug |
3 |
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7876149 | Distinct functions of the Fc epsilon R1 gamma and beta subunits in the control of Fc epsilon R1-mediated tyrosine kinase activation and signaling responses in RBL-2H3 mast cells. | 1995 Feb 24 |
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7515887 | Activation of protein tyrosine kinase p72syk by Fc epsilon RI aggregation in rat basophilic leukemia cells. p72syk is a minor component but the major protein tyrosine kinase of pp72. | 1994 Jun 17 |
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7961959 | Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol. | 1994 Nov 25 |
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8034715 | The anti-ganglioside monoclonal antibody AA4 induces protein tyrosine phosphorylations, but not degranulation, in rat basophilic leukemia cells. | 1994 Jul 29 |
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