Title : Clustering of Syk is sufficient to induce tyrosine phosphorylation and release of allergic mediators from rat basophilic leukemia cells.

Pub. Date : 1995 Mar

PMID : 7532280






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Clustering of Syk is sufficient to induce tyrosine phosphorylation and release of allergic mediators from rat basophilic leukemia cells. Tyrosine spleen associated tyrosine kinase Rattus norvegicus
2 Early events induced upon cross-linking of Fc epsilon RI include tyrosine phosphorylation of Fc epsilon RI subunits and activation of the tyrosine kinase p72syk (Syk), which binds to tyrosine-phosphorylated Fc epsilon RI. Tyrosine spleen associated tyrosine kinase Rattus norvegicus
3 Early events induced upon cross-linking of Fc epsilon RI include tyrosine phosphorylation of Fc epsilon RI subunits and activation of the tyrosine kinase p72syk (Syk), which binds to tyrosine-phosphorylated Fc epsilon RI. Tyrosine spleen associated tyrosine kinase Rattus norvegicus
4 Consistent with this finding, clustering of Syk also induced the tyrosine phosphorylation of a profile of proteins, including phospholipase C-gamma 1 and mitogen-activated protein kinase, similar to that induced upon clustering of Fc epsilon RI. Tyrosine spleen associated tyrosine kinase Rattus norvegicus