Title : Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling.

Pub. Date : 1997 Dec 19

PMID : 9405454






2 Functional Relationships(s)
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1 Although Src family kinases are activated by FcepsilonRI stimulation and tyrosine-phosphorylate the receptor subunits, the activation and tyrosine phosphorylation of Pyk2 were downstream of Syk. Tyrosine spleen associated tyrosine kinase Rattus norvegicus
2 Therefore, the FcepsilonRI-induced tyrosine phosphorylation of Pyk2 is downstream of Syk and may play a role in cell secretion. Tyrosine spleen associated tyrosine kinase Rattus norvegicus