Folic Acid

replication factor C subunit 1 ; Homo sapiens

57 Article(s)
Pub. Year
#Total Relationships
1 32820034 CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. 2021 Jul 1
2 33913025 Association of maternal folate use and reduced folate carrier gene polymorphisms with the risk of congenital heart disease in offspring. 2021 Oct 3
3 34769063 Targeting Folate Metabolism Is Selectively Cytotoxic to Glioma Stem Cells and Effectively Cooperates with Differentiation Therapy to Eliminate Tumor-Initiating Cells in Glioma Xenografts. 2021 Oct 27 2
4 31223065 Folate pathway genes linked to mitochondrial biogenesis and respiration are associated with outcome of patients with stage III colorectal cancer. 2019 Jun 1
5 31482954 Can the genetic polymorphisms of the folate metabolism have an influence in the polycystic ovary syndrome? 2019 1
6 28994615 MTRR A66G, RFC1 G80A, and MTHFR C677T and A1298C Polymorphisms and Disease Activity in Mexicans with Rheumatoid Arthritis Treated with Methotrexate. 2017 Nov 1
7 25536437 RFC-1 80G>A polymorphism in case-mother/control-mother dyads is associated with risk of nephroblastoma and neuroblastoma. 2015 Feb 2
8 25758536 Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: a randomized, double blind, crossover study. 2015 May 7
9 24333266 Epigenetic modulation of RFC1, MHC2TA and HLA-DR in systemic lupus erythematosus: association with serological markers and six functional polymorphisms of one-carbon metabolic pathway. 2014 Feb 15 2
10 24554143 Serum folic acid and RFC A80G polymorphism in Alzheimer's disease and vascular dementia. 2014 Feb 2
11 24597986 Association between reduced folate carrier G80A polymorphism and methotrexate toxicity in childhood acute lymphoblastic leukemia: a meta-analysis. 2014 Dec 1
12 24995314 A pilot study evaluating the contribution of SLC19A1 (RFC-1) 80G>a polymorphism to Alzheimer's disease in Italian Caucasians. 2014 1
13 23857226 The reduced folate carrier (RFC-1) 80A>G polymorphism and maternal risk of having a child with Down syndrome: a meta-analysis. 2013 Jul 5 2
14 21878957 Association of MTHFR and RFC1 gene polymorphism with hyperhomocysteinemia and its modulation by vitamin B12 and folic acid in an Indian population. 2012 Jan 1
15 22975209 Reduced folate carrier A80G polymorphism and susceptibility to neural tube defects: a meta-analysis. 2012 Dec 1 2
16 20468076 A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism. 2010 Sep 1
17 20501616 Pralatrexate is synergistic with the proteasome inhibitor bortezomib in in vitro and in vivo models of T-cell lymphoid malignancies. 2010 Jul 15 1
18 18258338 Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease. 2009 Oct 1
19 18602821 Time course gene expression in the one-carbon metabolism network using HepG2 cell line grown in folate-deficient medium. 2009 Apr 2
20 19105199 Association of reduced folate carrier gene polymorphism and maternal folic acid use with neural tube defects. 2009 Sep 5 1
21 19650776 The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among women. 2009 Sep 6
22 17531458 Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo. 2008 Feb 2
23 18022874 Correlation of polymorphism of MTHFRs and RFC-1 genes with neural tube defects in China. 2008 Jan 1
24 18400109 Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. 2008 Apr 9 3
25 18629538 Reduced folate carrier 80A-->G polymorphism, plasma folate, and risk of placental abruption. 2008 Sep 1
26 18823966 Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates. 2008 Dec 1
27 18842806 Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. 2008 Oct 1
28 19172696 The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study. 2008 5
29 17325736 Reduced folate carrier-1 80G>A polymorphism affects methotrexate treatment outcome in rheumatoid arthritis. 2007 Dec 3
30 17329909 Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells. 2007 Feb 25 1
31 17615259 Folate receptor and human reduced folate carrier expression in HepG2 cell line exposed to fumonisin B1 and folate deficiency. 2007 Nov 1
32 16596679 Folate gene polymorphisms and the risk of Down syndrome pregnancies in young Italian women. 2006 May 15 1
33 16962770 Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population. 2006 Dec 3
34 15799025 Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population. 2005 Jun 1
35 15952116 Interaction between maternal periconceptional supplementation of folic acid and reduced folate carrier gene polymorphism of neural tube defects. 2005 Jun 3
36 16086047 [Epidemiological study on reduced folate carrier gene(RFC1 A80G) polymorphism and other risk factors of neural tube defects]. 2005 Aug 18 1
37 16096989 Stereoselectivity of the reduced folate carrier in Caco-2 cells. 2005 Oct 1
38 16122883 Low expression of reduced folate carrier-1 and folylpolyglutamate synthase correlates with lack of a deleted in colorectal carcinoma mRNA splice variant in normal-appearing mucosa of colorectal carcinoma patients. 2005 1
39 15639995 [Advances in the study of the etiologic relationship between reduced folate carrier gene (RFC1) and neural tube and craniofacial defects]. 2004 Mar 3
40 15769366 [Study on the association between reduced folate carrier gene polymorphism and congenital heart defects and cleft lip with or without cleft palate]. 2004 Dec 1
41 12519783 Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells. 2003 Mar 14 2
42 12707400 Effect of glutamate carboxypeptidase II and reduced folate carrier polymorphisms on folate and total homocysteine concentrations in dialysis patients. 2003 May 1
43 12753319 Effects of the glutamate carboxypeptidase II (GCP2 1561C>T) and reduced folate carrier (RFC1 80G>A) allelic variants on folate and total homocysteine levels in kidney transplant patients. 2003 Jun 2
44 12854905 Activity of a novel anti-folate (PDX, 10-propargyl 10-deazaaminopterin) against human lymphoma is superior to methotrexate and correlates with tumor RFC-1 gene expression. 2003 Jun 2
45 12855225 Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. 2003 Jul 1
46 14676127 Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients. 2003 Dec 1 2
47 11266438 Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs. 2001 Mar 30 2
48 11306683 Mutational analysis of the functional role of conserved arginine and lysine residues in transmembrane domains of the murine reduced folate carrier. 2001 May 2
49 11427193 Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis. 2001 Jul 2 2
50 10648641 Role of the amino acid 45 residue in reduced folate carrier function and ion-dependent transport as characterized by site-directed mutagenesis. 2000 Feb 4