Tyrosine

ret proto-oncogene ; Homo sapiens







139 Article(s)
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1 33768672 Proteomic analysis of tyrosine phosphorylation induced by exogenous expression of oncogenic kinase fusions identified in lung adenocarcinoma. 2021 May 1
2 31477837 A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis. 2020 Jan 1
3 31711124 REToma: a cancer subtype with a shared driver oncogene. 2020 Apr 22 4
4 31988000 RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies. 2020 Apr 4
5 32034713 Receptor Tyrosine Kinases: Principles and Functions in Glioma Invasion. 2020 1
6 32062451 PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential. 2020 Feb 21 1
7 32064171 Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action. 2020 1
8 32816064 Intracellular RET signaling pathways activated by GDNF. 2020 Oct 1
9 31364476 RET S409Y Germline Mutation and Associated Medullary Thyroid Carcinoma. 2019 Oct 3
10 31576143 Targeted Therapy For RET-Rearranged Non-Small Cell Lung Cancer: Clinical Development And Future Directions. 2019 1
11 31715421 RET fusions in solid tumors. 2019 Dec 7
12 31754623 Plasma receptor tyrosine kinase RET in pulmonary arterial hypertension diagnosis and differentiation. 2019 Oct 3
13 28460442 EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression. 2017 Apr 18 1
14 26765577 A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A. 2016 Mar 2
15 27226544 Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction. 2016 Jul 29 3
16 24022366 To bud or not to bud: the RET perspective in CAKUT. 2014 Apr 1
17 24437351 The involvement of reactive oxygen species derived from NADPH oxidase-1 activation on the constitutive tyrosine auto-phosphorylation of RET proteins. 2014 Apr 8
18 24779031 Computational delineation of tyrosyl-substrate recognition and catalytic landscapes by the epidermal growth factor receptor tyrosine kinase domain. 2014 Jul 1
19 23329180 Targeting RET to induce medullary thyroid cancer cell apoptosis: an antagonistic interplay between PI3K/Akt and p38MAPK/caspase-8 pathways. 2013 May 2
20 24061856 A novel noncanonical signaling pathway for the μ-opioid receptor. 2013 Dec 1
21 24386391 Tyrosine phosphorylation allows integration of multiple signaling inputs by IKKβ. 2013 1
22 22811067 Dimerization in the Grb7 protein. 2012 Aug 4
23 22973453 Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors. 2012 1
24 22982678 New insights into Dok-4 PTB domain structure and function. 2012 Oct 12 1
25 21110809 Development of RET kinase inhibitors for targeted cancer therapy. 2011 1
26 21454698 Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism. 2011 May 13 6
27 21741956 Interplay between Ret and Fap-1 regulates CD95-mediated apoptosis in medullary thyroid cancer cells. 2011 Oct 1 1
28 21807000 Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR. 2011 Sep 12 1
29 20442138 The RET51/FKBP52 complex and its involvement in Parkinson disease. 2010 Jul 15 2
30 20682772 Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase. 2010 Oct 8 5
31 20973951 Tyrosine phosphorylation of Grb14 by Tie2. 2010 Oct 25 2
32 19029224 Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474. 2009 Mar 1
33 19060924 XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway. 2009 Feb 19 4
34 19320641 RET protein promotes non-adherent growth of NB-39-nu neuroblastoma cell line. 2009 Jun 1
35 18189271 Cell migration by a FRS2-adaptor dependent membrane relocation of ret receptors. 2008 Jun 1 1
36 18248647 The Y606C RET mutation causes a receptor gain of function. 2008 Aug 1
37 18273880 RET Gly691Ser mutation is associated with primary vesicoureteral reflux in the French-Canadian population from Quebec. 2008 May 2
38 18316596 A novel RET kinase-beta-catenin signaling pathway contributes to tumorigenesis in thyroid carcinoma. 2008 Mar 1 2
39 18394855 Gas1 reduces Ret tyrosine 1062 phosphorylation and alters GDNF-mediated intracellular signaling. 2008 Aug 2
40 18418222 Sustained clinical responses to tyrosine kinase inhibitor sunitinib in thyroid carcinoma. 2008 Jun 1
41 18682802 Receptor tyrosine kinase (RTK) mediated tyrosine phosphor-proteome from Drosophila S2 (ErbB1) cells reveals novel signaling networks. 2008 Aug 6 3
42 17209045 Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation. 2007 Mar 2 2
43 17471236 SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signaling. 2007 Oct 4 1
44 17490619 Crosstalk between VEGF-A/VEGFR2 and GDNF/RET signaling pathways. 2007 Jun 29 2
45 17548251 Effect of Sirpalpha1 on the expression of nuclear factor-kappa B in hepatocellular carcinoma. 2007 Jun 3
46 17599050 RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface. 2007 Dec 13 2
47 17715395 Monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer. 2007 Dec 1
48 17761947 Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC). 2007 Dec 2
49 16484222 Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene. 2006 Apr 14 4
50 16756963 Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1. 2006 Aug 14 1