Title : RET fusions in solid tumors.

Pub. Date : 2019 Dec

PMID : 31715421






7 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 RET fusions or rearrangements are somatic juxtapositions of 5" sequences from other genes with 3" RET sequences encoding tyrosine kinase. Tyrosine ret proto-oncogene Homo sapiens
2 RET fusions or rearrangements are somatic juxtapositions of 5" sequences from other genes with 3" RET sequences encoding tyrosine kinase. Tyrosine ret proto-oncogene Homo sapiens
3 Tyrosine kinase inhibitors are drugs that target kinases such as RET in RET-driven (RET-mutation or RET-fusion-positive) disease. Tyrosine ret proto-oncogene Homo sapiens
4 Tyrosine kinase inhibitors are drugs that target kinases such as RET in RET-driven (RET-mutation or RET-fusion-positive) disease. Tyrosine ret proto-oncogene Homo sapiens
5 Tyrosine kinase inhibitors are drugs that target kinases such as RET in RET-driven (RET-mutation or RET-fusion-positive) disease. Tyrosine ret proto-oncogene Homo sapiens
6 Tyrosine kinase inhibitors are drugs that target kinases such as RET in RET-driven (RET-mutation or RET-fusion-positive) disease. Tyrosine ret proto-oncogene Homo sapiens
7 RET fusions provide a viable therapeutic target for oncologic treatment, and further study is warranted into the prevalence and pathogenesis of RET fusions as well as development of current and new tyrosine kinase inhibitors. Tyrosine ret proto-oncogene Homo sapiens