Kynurenine

indoleamine 2,3-dioxygenase 1 ; Homo sapiens







575 Article(s)
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1 33135582 Why Severe COVID-19 Patients Are at Greater Risk of Developing Depression: A Molecular Perspective. 2022 Feb 2
2 34269660 Tryptophan Metabolism in Atherosclerosis and Diabetes. 2022 2
3 34714577 Stemness and immune evasion conferred by the TDO2-AHR pathway are associated with liver metastasis of colon cancer. 2022 Jan 1
4 34752953 Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and PROTAC-based degraders for cancer therapy. 2022 Jan 5 4
5 34847078 Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy. 2022 Jan 18 1
6 35046097 Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia. 2022 Apr 1 3
7 35051612 Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through GAPDH- and Hsp90-dependent control of their heme levels. 2022 Feb 20 1
8 35057467 Tryptophan Metabolism Is Associated with BMI and Adipose Tissue Mass and Linked to Metabolic Disease in Pediatric Obesity. 2022 Jan 11 2
9 35085834 Role of indoleamine 2,3-dioxygenase 1 (IDO1) and kynurenine pathway in the regulation of the aging process. 2022 Mar 2
10 35090836 Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms. 2022 Feb 1
11 35120895 Myricetin inhibits interferon-γ-induced PD-L1 and IDO1 expression in lung cancer cells. 2022 Mar 1
12 35150740 Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation. 2022 Mar 2
13 35173722 Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and Perspectives. 2022 2
14 35187162 T Lymphocyte Infiltration in Association with IDO1 Expression in Resected Lung Adenocarcinoma and Normal Adjacent Lung Tissues. 2022 4
15 35203299 Hypothesis: Emerging Roles for Aryl Hydrocarbon Receptor in Orchestrating CoV-2-Related Inflammation. 2022 Feb 13 4
16 35245456 Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling. 2022 Mar 3 2
17 35294258 Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses. 2022 Mar 16 1
18 35358772 Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase. 2022 May 5 4
19 35371018 Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression? 2022 3
20 35371054 Indoleamine 2, 3-Dioxygenase 1 Mediates Survival Signals in Chronic Lymphocytic Leukemia via Kynurenine/Aryl Hydrocarbon Receptor-Mediated MCL1 Modulation. 2022 4
21 35413710 The Role of Kynurenines Produced by Indolamine-2,3-Dioxygenase 1 in Sepsis. 2022 Apr 12 3
22 35458704 Curcumin Facilitates Aryl Hydrocarbon Receptor Activation to Ameliorate Inflammatory Astrogliosis. 2022 Apr 13 2
23 35466092 Proposed Pathway Linking Respiratory Infections with Depression. 2022 May 31 1
24 35510301 Extracellular adenosine triphosphate induces IDO and IFNγ expression of human periodontal ligament cells through P2 X7 receptor signaling. 2022 May 4 1
25 35545044 A pan-cancer metabolic atlas of the tumor microenvironment. 2022 May 10 1
26 35582948 Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency in Vascular Smooth Muscle Cells Exacerbates Arterial Calcification. 2022 Jun 14 1
27 35604497 Elevated serum levels of kynurenine pathway metabolites in patients with Behçet disease. 2022 Jun 2
28 32707579 Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients. 2021 Jan 1
29 32974990 Characterization of Apo-Form Selective Inhibition of Indoleamine 2,3-Dioxygenase*. 2021 Feb 2 2
30 33132153 The effect of environmental pollution on immune evasion checkpoints of SARS-CoV-2. 2021 Jan 1
31 33212094 Indoleamine and tryptophan 2,3-dioxygenases as important future therapeutic targets. 2021 May 1
32 33222028 The evaluation of serum tryptophan and kynurenine levels in patients with obstructive sleep apnea syndrome. 2021 Sep 1
33 33298590 Preclinical Characterization of Linrodostat Mesylate, a Novel, Potent, and Selective Oral Indoleamine 2,3-Dioxygenase 1 Inhibitor. 2021 Mar 1
34 33328638 Anti-tumour immunity induces aberrant peptide presentation in melanoma. 2021 Feb 2
35 33373218 Conformational Plasticity in Human Heme-Based Dioxygenases. 2021 Feb 3 2
36 33390854 The IFN-γ-IDO1-kynureine pathway-induced autophagy in cervical cancer cell promotes phagocytosis of macrophage. 2021 1
37 33410234 Tryptophan 2,3-dioxygenase in tumor cells is associated with resistance to immunotherapy in renal cell carcinoma. 2021 Mar 2
38 33418116 Tryptophan and indole metabolism in immune regulation. 2021 Jun 3
39 33422134 Inflammatory cytokines-stimulated human muscle stem cells ameliorate ulcerative colitis via the IDO-TSG6 axis. 2021 Jan 9 2
40 33422142 Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer's disease. 2021 Jan 9 4
41 33460767 Role of tryptophan metabolism in cancers and therapeutic implications. 2021 Mar 4
42 33529725 The footprint of kynurenine pathway in every cancer: a new target for chemotherapy. 2021 Apr 5 2
43 33539022 Indoleamine 2,3-Dioxygenase Activity-Induced Acceleration of Tumor Growth, and Protein Kinases-Related Novel Therapeutics Regimens. 2021 2
44 33557523 Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. 2021 Feb 25 2
45 33557876 What is the prospect of indoleamine 2,3-dioxygenase 1 inhibition in cancer? Extrapolation from the past. 2021 Feb 8 2
46 33609532 Interactions of human mesenchymal stromal cells with peripheral blood mononuclear cells in a Mitogenic proliferation assay. 2021 May 2
47 33675038 Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3-dioxygenase 1 with functional effects on T cell priming. 2021 Jun 3
48 33718949 Plasma Kynurenine-to-Tryptophan Ratio, a Highly Sensitive Blood-Based Diagnostic Tool for Tuberculosis in Pregnant Women Living With Human Immunodeficiency Virus (HIV). 2021 Sep 15 2
49 33737337 GD2 redirected CAR T and activated NK-cell-mediated secretion of IFNγ overcomes MYCN-dependent IDO1 inhibition, contributing to neuroblastoma cell immune escape. 2021 Mar 2
50 33741464 Discovery of 5-(N-hydroxycarbamimidoyl) benzofuran derivatives as novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. 2021 May 15 2