Pub. Date : 2022 Feb
PMID : 33135582
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We posit that a phenomenon known as cytokine storm dramatically activates the enzyme indoleamine 2,3-dioxygenase (IDO-1), resulting in the increase in kynurenine metabolites. | Kynurenine | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
2 | Kynurenine is metabolized by IDO-1 in the brain, producing chemokines, in which a prolonged exposure may result long-term brain impairment. | Kynurenine | indoleamine 2,3-dioxygenase 1 | Homo sapiens |