| 1 |
33460183 | Validation of a HPLC method for quantification of midazolam in rat plasma: Application during a Maytenus ilicifolia-drug interaction study. | 2021 Mar |
4 |
| 2 |
34388602 | UPLC-MS/MS analysis of the Michaelis-Menten kinetics of CYP3A-mediated midazolam 1'- and 4-hydroxylation in rat brain microsomes. | 2021 Aug 15 |
5 |
| 3 |
34734526 | Involvement of the Parathyroid Hormone-Related Protein on Changes in the CYP3A Expression in Cancer Cachexia. | 2021 Dec 6 |
1 |
| 4 |
31403362 | Effects of dexamethasone to reverse decreased hepatic midazolam metabolism in rats with acute renal failure. | 2020 May |
1 |
| 5 |
32394829 | Evaluation of the Effects of Maytenus ilicifolia on the Activities of Cytochrome P450 3A and P-glycoprotein. | 2020 |
2 |
| 6 |
32879206 | Effect of Chronic Kidney Disease on Hepatic Clearance of Drugs in Rats. | 2020 |
1 |
| 7 |
32915856 | Involvement of NF-κB in the reversal of CYP3A down-regulation induced by sea buckthorn in BCG-induced rats. | 2020 |
2 |
| 8 |
30714842 | Conflicting alterations in hepatic expression of CYP3A and enzyme kinetics in rats exposed to 5-fluorouracil: relevance to pharmacokinetics of midazolam. | 2019 Dec |
7 |
| 9 |
31579949 | Effect of renal ischaemia/reperfusion-induced acute kidney injury on pharmacokinetics of midazolam in rats. | 2019 Dec |
4 |
| 10 |
28843775 | Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism. | 2017 Dec 1 |
1 |
| 11 |
28867721 | Inhibitory Effect of Oxethazaine on Midazolam Metabolism in Rats. | 2017 |
2 |
| 12 |
29878735 | [Optimization of midazolam dosage and pharmacokinetics of CYP3A probe substrate in rats]. | 2016 May |
4 |
| 13 |
25430017 | Change in pharmacokinetic behavior of intravenously administered midazolam due to increased CYP3A2 expression in rats treated with menthol. | 2015 Apr |
1 |
| 14 |
25953268 | Induction of CYP3A by morroniside in rats. | 2015 Apr |
2 |
| 15 |
26053556 | Decreased elimination clearance of midazolam by doxorubicin through reductions in the metabolic activity of hepatic CYP3A in rats. | 2015 |
1 |
| 16 |
24486211 | Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats. | 2014 Mar 14 |
1 |
| 17 |
25548518 | Xyloketal B, a marine compound, acts on a network of molecular proteins and regulates the activity and expression of rat cytochrome P450 3a: a bioinformatic and animal study. | 2014 |
1 |
| 18 |
23589122 | Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats. | 2013 Sep |
2 |
| 19 |
23589366 | Time-dependent interaction of ritonavir in chronic use: the power balance between inhibition and induction of P-glycoprotein and cytochrome P450 3A. | 2013 Jun |
2 |
| 20 |
23710212 | Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats. | 2013 |
2 |
| 21 |
24345506 | Reversing effects of silybin on TAA-induced hepatic CYP3A dysfunction through PXR regulation. | 2013 Nov |
1 |
| 22 |
22339466 | Effects of Phyllanthus amarus on the pharmacokinetics of midazolam and cytochrome P450 activities in rats. | 2012 Jul |
3 |
| 23 |
22351566 | Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure. | 2012 Jan |
1 |
| 24 |
21155816 | Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy. | 2011 Jan |
6 |
| 25 |
21358120 | In vivo inhibition of CYP3A-mediated midazolam metabolism by anchusan in rats. | 2011 |
2 |
| 26 |
21868471 | Cardiac arrest and therapeutic hypothermia decrease isoform-specific cytochrome P450 drug metabolism. | 2011 Dec |
2 |
| 27 |
20448858 | Inhibitory effects of schisandrin A and schisandrin B on CYP3A activity. | 2010 Apr |
1 |
| 28 |
20503931 | Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats. | 2010 May |
1 |
| 29 |
20637580 | A pharmacodynamic-pharmacokinetic (PD-PK) study on the effects of Danshen (Salvia miltiorrhiza) on midazolam, a model CYP3A probe substrate, in the rat. | 2010 Sep |
1 |
| 30 |
20831533 | Effect of plasma uric acid on pharmacokinetics of cyclosporine A in living-related renal transplant recipients and pharmacokinetic study in rats with experimental hyperuricaemia. | 2010 Jun |
1 |
| 31 |
19219745 | Development of an optimized procedure for the preparation of rat intestinal microsomes: comparison of hepatic and intestinal microsomal cytochrome P450 enzyme activities in two rat strains. | 2009 Jan |
1 |
| 32 |
19237454 | Limited sampling strategy in rats to predict the inhibited activities of hepatic CYP3A. | 2009 Jul |
4 |
| 33 |
19702545 | Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure. | 2009 Aug |
1 |
| 34 |
18082981 | Inhibitory effect of docosahexaenoic acid (DHA) on the intestinal metabolism of midazolam: in vitro and in vivo studies in rats. | 2008 Mar 3 |
1 |
| 35 |
18329630 | Quercetin pretreatment increases the bioavailability of pioglitazone in rats: involvement of CYP3A inhibition. | 2008 Apr 15 |
1 |
| 36 |
19048780 | [A limited sampling strategy of phenotyping probe midazolam to predict inhibited activities of hepatic CYP3A in rats]. | 2008 Sep |
4 |
| 37 |
17050652 | Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats. | 2007 Jan |
2 |
| 38 |
17287587 | Effects of continuous ingestion of herbal teas on intestinal CYP3A in the rat. | 2007 Feb |
1 |
| 39 |
17827786 | Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis. | 2007 Aug |
1 |
| 40 |
16019953 | Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug-drug interaction model rats. | 2005 Apr |
1 |
| 41 |
16079494 | Time-dependent induction of midazolam-1-hydroxylation enzymes in rats treated with St. John's wort. | 2005 Aug |
3 |
| 42 |
14600803 | Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress? | 2004 Mar |
1 |
| 43 |
15319324 | The effect of anesthesia and surgery on CYP3A activity in rats. | 2004 Nov |
1 |
| 44 |
15370957 | Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. II: establishment and evaluation of dexamethasone-pretreated female rats. | 2004 May |
3 |
| 45 |
12837492 | Impact of Solutol HS 15 on the pharmacokinetic behavior of midazolam upon intravenous administration to male Wistar rats. | 2003 Jul |
1 |
| 46 |
12920171 | Application of compartmental modeling to an examination of in vitro intestinal permeability data: assessing the impact of tissue uptake, P-glycoprotein, and CYP3A. | 2003 Sep |
1 |
| 47 |
12167482 | Role of temperature on protein and mRNA cytochrome P450 3A (CYP3A) isozymes expression and midazolam oxidation by cultured rat precision-cut liver slices. | 2002 Aug 15 |
3 |
| 48 |
12487727 | Differential induction of midazolam metabolism in the small intestine and liver by oral and intravenous dexamethasone pretreatment in rat. | 2002 Nov |
1 |
| 49 |
11714877 | Midazolam is a phenobarbital-like cytochrome p450 inducer in rats. | 2001 Dec |
4 |
| 50 |
11786231 | Reoxygenation after cold hypoxic storage of cultured precision-cut rat liver slices: effects on cellular metabolism and drug biotransformation. | 2001 Dec 19 |
1 |