Title : Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis.

Pub. Date : 2007 Aug

PMID : 17827786






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intestinal CYP3A activities (midazolam 1"-hydroxylation and 7-benzyloxy-4-(trifluoromethyl)-coumarin 7-hydroxylation) in AA rats were significantly decreased compared with those in normal rats, with marked decrease observed in the upper segment of intestine. Midazolam cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus