Title : Effect of renal ischaemia/reperfusion-induced acute kidney injury on pharmacokinetics of midazolam in rats.

Pub. Date : 2019 Dec

PMID : 31579949






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1 OBJECTIVES: This study aimed to investigate the effects of renal ischaemia/reperfusion (I/R)-induced acute kidney injury (AKI) on the distribution of midazolam (MDZ), a probe drug for cytochrome P450 3A (CYP3A) activity. Midazolam cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus
2 OBJECTIVES: This study aimed to investigate the effects of renal ischaemia/reperfusion (I/R)-induced acute kidney injury (AKI) on the distribution of midazolam (MDZ), a probe drug for cytochrome P450 3A (CYP3A) activity. Midazolam cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus
3 OBJECTIVES: This study aimed to investigate the effects of renal ischaemia/reperfusion (I/R)-induced acute kidney injury (AKI) on the distribution of midazolam (MDZ), a probe drug for cytochrome P450 3A (CYP3A) activity. Midazolam cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus
4 OBJECTIVES: This study aimed to investigate the effects of renal ischaemia/reperfusion (I/R)-induced acute kidney injury (AKI) on the distribution of midazolam (MDZ), a probe drug for cytochrome P450 3A (CYP3A) activity. Midazolam cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus