| 1 |
33990932 | Pluripotent Stem Cell Derived Neurons as In Vitro Models for Studying Autosomal Recessive Parkinson's Disease (ARPD): PLA2G6 and Other Gene Loci. | 2021 |
4 |
| 2 |
34131139 | iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4. | 2021 Jun 15 |
1 |
| 3 |
34143707 | The design and discovery of phospholipase A2 inhibitors for the treatment of inflammatory diseases. | 2021 Nov |
1 |
| 4 |
34207793 | iPLA2β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury. | 2021 Jun 9 |
2 |
| 5 |
34474084 | Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A2s. | 2021 |
2 |
| 6 |
34506510 | iPLA2-VIA is required for healthy aging of neurons, muscle, and the female germline in Drosophila melanogaster. | 2021 |
4 |
| 7 |
34831185 | Dynamic Role of Phospholipases A2 in Health and Diseases in the Central Nervous System. | 2021 Oct 30 |
1 |
| 8 |
34859139 | The roads to ferroptosis under homeostatic versus pathological conditions. | 2021 |
1 |
| 9 |
31689548 | Infantile onset progressive cerebellar atrophy and anterior horn cell Degeneration-A novel phenotype associated with mutations in the PLA2G6 gene. | 2020 Apr |
1 |
| 10 |
32010257 | Successful clinical application of pre-implantation genetic diagnosis for infantile neuroaxonal dystrophy. | 2020 Feb |
1 |
| 11 |
30905345 | Phospholipase A2 catalysis and lipid mediator lipidomics. | 2019 Jun |
1 |
| 12 |
31019507 | SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player. | 2019 |
1 |
| 13 |
31277247 | Possible Involvement of Intracellular Calcium-Independent Phospholipase A2 in the Release of Secretory Phospholipases from Mast Cells-Increased Expression in Ileal Mast Cells of Crohn's Disease. | 2019 Jul 3 |
1 |
| 14 |
31717968 | The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2. | 2019 Nov 11 |
1 |
| 15 |
29427237 | Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids. | 2018 May |
1 |
| 16 |
29472584 | The structure of iPLA2β reveals dimeric active sites and suggests mechanisms of regulation and localization. | 2018 Feb 22 |
2 |
| 17 |
30619057 | PLA2G6-Associated Neurodegeneration (PLAN): Review of Clinical Phenotypes and Genotypes. | 2018 |
2 |
| 18 |
28063488 | Analyses of Calcium-Independent Phospholipase A2beta (iPLA2β) in Biological Systems. | 2017 |
1 |
| 19 |
28602806 | The overall fatty acid absorption controlled by basolateral chylomicron excretion under regulation of p-JNK1. | 2017 Sep |
1 |
| 20 |
28618256 | Cigarette Smoke Regulates Calcium-Independent Phospholipase A2 Metabolic Pathways in Breast Cancer. | 2017 Aug |
1 |
| 21 |
26668131 | Disruption of Golgi morphology and altered protein glycosylation in PLA2G6-associated neurodegeneration. | 2016 Mar |
1 |
| 22 |
26857573 | Mice with Genetic Deletion of Group VIA Phospholipase A2β Exhibit Impaired Macrophage Function and Increased Parasite Load in Trypanosoma cruzi-Induced Myocarditis. | 2016 Apr |
1 |
| 23 |
26873633 | iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. | 2016 May |
3 |
| 24 |
27141409 | Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation. | 2016 |
1 |
| 25 |
27320659 | Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. | 2016 Oct 15 |
1 |
| 26 |
24870368 | A case of infantile neuroaxonal dystrophy of neonatal onset. | 2015 Mar |
1 |
| 27 |
25041493 | Reduced activities of phospholipases A2 in platelets of drug-naïve bipolar disorder patients. | 2015 Feb |
3 |
| 28 |
25624474 | Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates. | 2015 Feb 10 |
1 |
| 29 |
26001724 | Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction. | 2015 Jul |
1 |
| 30 |
24791136 | Calcium-independent phospholipase A₂, group VIA, is critical for RPE cell survival. | 2014 |
1 |
| 31 |
25072959 | The arachidonic acid-LTB4-BLT2 pathway enhances human B-CLL aggressiveness. | 2014 Nov |
1 |
| 32 |
25186013 | Enhanced breast cancer cell adherence to the lung endothelium via PAF acetylhydrolase inhibition: a potential mechanism for enhanced metastasis in smokers. | 2014 Nov 15 |
1 |
| 33 |
25654966 | IPLA2 mRNA expression by human neutrophils in type 2 diabetes and chronic periodontitis. | 2014 Oct |
1 |
| 34 |
22903185 | Neuronal phospholipid deacylation is essential for axonal and synaptic integrity. | 2013 Mar |
1 |
| 35 |
23701211 | Mechanism-based inhibition of iPLA2β demonstrates a highly reactive cysteine residue (C651) that interacts with the active site: mass spectrometric elucidation of the mechanisms underlying inhibition. | 2013 Jun 18 |
2 |
| 36 |
23736975 | Dystonic opisthotonus: a "red flag" for neurodegeneration with brain iron accumulation syndromes? | 2013 Sep |
1 |
| 37 |
23791636 | Specific roles for Group V secretory PLA₂ in retinal iron-induced oxidative stress. Implications for age-related macular degeneration. | 2013 Aug |
1 |
| 38 |
23916152 | New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2. | 2013 Sep 15 |
1 |
| 39 |
25337551 | Global Inactivation of the Pla2g6 Gene in Mice Does Not Cause Dyslipidemia under Chow or High-fat Diet Conditions. | 2013 Sep |
2 |
| 40 |
22498046 | A radioenzymatic assay to identify three groups of phospholipase A(2) in platelets. | 2012 Apr |
5 |
| 41 |
22685677 | Maintenance of synaptic stability requires calcium-independent phospholipase A₂ activity. | 2012 |
2 |
| 42 |
23279172 | Alterations of brain membranes in schizophrenia: impact of phospholipase A(2). | 2012 |
1 |
| 43 |
20086008 | Role of calcium-independent phospholipase A2beta in high glucose-induced activation of RhoA, Rho kinase, and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals. | 2010 Mar 19 |
1 |
| 44 |
20369880 | Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2. | 2010 May 13 |
1 |
| 45 |
20464283 | Study of association between genetic polymorphisms of phospholipase A2 enzymes and Alzheimer's disease. | 2010 Apr |
1 |
| 46 |
20530749 | Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development. | 2010 Oct |
1 |
| 47 |
20584031 | Novel splice-site mutations and a large intragenic deletion in PLA2G6 associated with a severe and rapidly progressive form of infantile neuroaxonal dystrophy. | 2010 Nov |
2 |
| 48 |
20886109 | Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism. | 2010 Sep 23 |
2 |
| 49 |
19074824 | Eicosanoid signalling pathways in the heart. | 2009 May 1 |
1 |
| 50 |
19225567 | Two chromogranin a-derived peptides induce calcium entry in human neutrophils by calmodulin-regulated calcium independent phospholipase A2. | 2009 |
1 |